don't take otezla if you are allergic to any of its ingredients. otezla may increase... ...the risk of depression. tell your doctor if you have a history of depression... ...or suicidal thoughts, or if these feelings develop. some people taking otezla reported weight loss. your doctor should monitor your weight and may stop treatment. side effects may include diarrhea, nausea, upper respiratory tract infection, and headache. tell your doctor about all the medicines you take and if you're pregnant or planning to be. ask your doctor about otezla today. otezla. show more of you. whether your car is a new car an old car a big car a small car a car that looks kind of plain a car that looks kind of like a plane a red car a white car a blue car a red white and blue car a green car a city car a country car this car, seriously this car a clean car, a dirty car