>> as dana mentioned, the conversations start, here are the treatment options, here are the likelihood of having some benefit from these treatment options and here's the toll those treatments are going to take on your body. and john, it's a constant balance after that. the decision at this point really comes down to are these treatments working, are they continuing to affect the tumor and actually shrink the tumor, and what is the toll that it's taking on my body? does the risk benefit still play out the are the benefits greater than the risks, and i think it's a discussion of probably some 13 months, but this is an inflection point where they say that's no longer the case. the benefits are no longer greater than the risks. >> some colleagues who have served with him for a very, very long time, what have you heard? >> yeah, what is remarkable about senator mccain is that he's a throwback to an era which