Argentina and Colombia had been chosen as co-hosts in 2019 to oversee a tournament that was originally planned to include 12 teams (the 10 CONMEBOL members and guests Qatar and Colombia).
But in 2020 the Copa was suspended for 12 months in the midst of the first wave of the coronavirus pandemic.
The situation in Colombia was further complicated by a wave of anti-government protests across the country and violent police reaction, with more than 60 people killed according to NGO estimates.
CONMEBOL stripped Colombia of hosting duties on May 21 and on Sunday announced that Argentina was also stepping down, after top government figures in the country voiced their doubts that the tournament could go ahead due to the current public health crisis.