LAFC will seek to be the first MLS team to be crowned in this tournament since the Galaxy, also from Los Angeles, won it in 2000.
LAFC will face Tigres UANL in the final will on Tuesday night in the same city, where the resumption of the tournament, interrupted in March by the pandemic, was concentrated.
Vela's team, which previously eliminated León and Cruz Azul on their way to the final, will try to beat Tigres to put an end to the dominance of the Mexican teams, which have been champions uninterruptedly since 2006.
The last non-Mexican team to be crowned at CONCACAF was Costa Rica's Saprissa in 2005.