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The guidance is not binding but most provincial governments have indicated they were waiting for the information before setting their policies for second doses.
Manitoba didn’t wait for the report to be published, announcing Monday they would offer AstraZeneca recipients Pfizer or Moderna if they wanted.
Quebec currently recommends getting the same vaccine twice but says with informed consent people who got AstraZeneca first can get Pfizer or Moderna.
The province is expected to update this later in the week, along with shortening the wait to get second doses of mRNA vaccines.
NACI’s advice comes after interim results were published in May from two studies looking at mixing and matching vaccines.