Plumes of smoke over the capital still over beirut. In central beirut, a massive overnight Air Strike killed nine people, in a multistorey building, Housing A Hezbollah affiliated health centre, near the lebanese parliament building. Lebanon says paramedics are among the dead. While the World Health Organization says 28 Health Workers have been killed in the past day. As the conflict escalates, more people are on the move well talk in a few minutes to the Un Agency organising aid in beirut. Meanwhile, the Lebanese Army says, that two of its soldiers have been killed, by israel in separate incidents in southern lebanon. I want to return to Whatjoe Biden has been saying because he responded to questions thrown at him yesterday saying of course the us did not support any potential israeli strikes on nuclear facilities. He was asked today whether there are discussions about israel and Irans Oil facilities and his answer was we are discussing that possibility and that resulted in a spike of Oil Prices of 5 as concerns grow about what we might see in the coming days. A spike of Oil Prices at 5 with Joe Biden saying discussions are being carried out with israel about potentially striking Irans Oil facilities. We can return to what is happening on the borders in lebanon. Our middle East Correspondent Nick beake is in northern israel. More israeli tanks being taken towards the border with lebanon. That is a reflection of the way the israelis are intensifying this operation against hezbollah. I say operation it is a mission now, and they insist its made up of lots of separate targeted operations, they say. So teams going in and then in some cases retreating. But certainly it does seem to be gathering pace in terms to be gathering pace. In terms of a Snapshot Ofjust where we are, i think in terms of what we heard in the skies above us, so far today, that has been considerably less than yesterday. But of course, thats just a snapshot of one particular location, because the Israeli Army is saying that its carried out a lot of strikes in the past day or so. Just as i say that there is a helicopter, i think, in the sky and carrying out more than 200 assaults, mainly in the south of lebanon. And once again, the israelis saying that they are targeting hezbollah positions. But at the same time, we have had these reports, of course, of civilians being caught in this, and also that the Lebanese Army saying today that two of their soldiers have been killed because of israeli fire. And in one case, they fired back. And thats the first time weve seen that sort of exchange between the Lebanese Army, which of course is separate from hezbollah, and the israeli forces. We will try to flesh out what is being discussed in various elements of the story. Lets speak to the israeli Journalist And Author gideon levy. Hes a columnist with the newspaper haaretz. And joins us from tel aviv. Welcome. A former israeli Prime Minister said this was the best opportunity in 50 years to change the face of the middle east. Is that the prevailing narrative amongst the administration there . Unfortunately, it is the prevailing narrative and unfortunately even more so it is a false narrative because war is never an opportunity. It always has ended with big disappointment if not a fiasco. Israel thinks still that getting into lebanon will sort the problem of hezbollah, by getting into gaza will solve the problem with hamas. In both cases it failed. Israel is one yearin cases it failed. Israel is one year in Gaza And Nothing was solved. And now it will repeat its same mistake also in lebanon, which is much more complicated because hezbollah is a much stronger organisation, and it is regrettable that israel again and again repeats its mistakes and again repeats its mistakes and the mindset still seems that war is a solution for anything. That war is a solution for anything that war is a solution for an hina. �. , anything. Benamin netanyahu would argue anything. Benjamin netanyahu would argue that anything. Benjamin netanyahu would argue that look anything. Benjamin netanyahu would argue that look what anything. Benjamin netanyahu| would argue that look what has happened over the past two weeks, they have taken out hezbollah� s leader, they have taken out half the fighters, they have taken out about half they have taken out about half the arsenal. Perhaps there is a way of ridding hezbollah from the map once and for all. That is his argument. The map once and for all. That is his argument. Once the map once and for all. That is his argument. Once and the map once and for all. Twat is his argument. Once and for all is only through diplomacy and political agreement. It will never be once and for all. Yes, there were impressive military achievements in the past two weeks but where do they lead us . Hezbollah is an organisation with 150,000 fighters. So you killed their commanders. There will be new ones, may be more dangerous. It will be a ceasefire finally. How can state live from war to war and do not present any of the vision but next war . B, the vision but next war . A final thought, the vision but next war . A finalthought, give me an the vision but next war . A final thought, give me an idea of the national mood, given what we have seen in lebanon, what we have seen in lebanon, what we have seen in lebanon, what we saw with the iranian missile sent over a couple of days ago, what do you think are the likely israeli targets in terms of that response to iran, the first wave of Potential Targets . The first wave of Potential Tar ets . ,. , targets . On one hand, there is overall support targets . On one hand, there is overall support in targets . On one hand, there is overall support in continuing i overall support in continuing the war in the Ground Operation in lebanon because people believe this will solve as you say once and for all. On the other hand, there is a heavy concern because everyone understands this will carry a heavy price. I would define their mood as heavy concern together with supporting the war, both in gaza and in lebanon. Gaining almost total support in israeli public opinion. I am support in israeli public opinion. Iam not support in israeli public opinion. I am not sure that is good news for israeli society. What do you expect them to target in iran when that movie is made . I target in iran when that movie is made . ~ ~ u, is made . I think the american president is made . I think the american president named is made . I think the american president named it, is made . I think the american president named it, so is made . I think the american president named it, so who i is made . I think the american | president named it, so who am i . They talk about aiming the oilfacilities, which i . They talk about aiming the oil facilities, which are a soft spot in iran and might create big damage to iran. But again a Vicious Circle because iran will retaliate and then what . ~ ,. , iran will retaliate and then what . ~ ~ iran will retaliate and then what . , ~ ~ iran will retaliate and then what . , ~. , what . Thank you. We can turn to another aspect what . Thank you. We can turn to another aspect of what . Thank you. We can turn to another aspect of what what . Thank you. We can turn to another aspect of what we what . Thank you. We can turn to another aspect of what we are i another aspect of what we are dealing with in the middle east, the humanitarian situation. Kristen knutson is head of the uns office for the Co Ordination of humanitarian affairs. Shejoins me live from beirut. We are grateful for your time. Give me a sense of the scale of what you are dealing with. Thank you for the opportunity to speak to you. The scale is simply catastrophic. We have over the past Year Seen People forced to flee from their homes and more immediately over the past two weeks, an Escalation the likes of which the country has not seen in 20 years. Two weeks ago, the explosions are pagers and Walkie Talkie devices which also affected civilians going about their daily life. The country was plunged into a health care crisis. Now with the Escalation of Air Strikes expanding to more parts of the country, people receiving displacement orders, sometimes with 15 minutes of notice and the middle of the night, three in the morning, instructions to flee their areas because Air Strikes are coming. We have had massive waves of displacement. Do people know where to go when they have these warnings and are given such a short space of time . , ~. ,. ,. , time . Do they know what to do . No, it is part time . Do they know what to do . No, it is part of time . Do they know what to do . No, it is part of the no, it is part of the difficulty we are dealing with is that there is not the manageable system when you have so little time, little warning to be able to direct people where to go so they are fleeing with what little they can carry, what they are wearing, basically, and they are trying to get away, to go to open spaces away from where they have been warned to leave. Our job as humanitarians working with the government of lebanon is to try to find them shelter. The government has thrown open more than 800 schools to provide shelter to almost 1 Million people who have been displaced and directly affected by the Escalation. The displaced and directly affected by the Escalation. By the Escalation. The World Health Organization, by the Escalation. The World Health Organization, their i by the Escalation. The world i health organization, their head said an hourago health organization, their head said an hour ago they will not be able to deliver shipments of trauma and treatments supplies due to Flight Restrictions in large amounts. Is it harder to get aid in and how much do you have . ~. , get aid in and how much do you have . ,. Get aid in and how much do you have . , w. , have . We have assistance on the round have . We have assistance on the ground that have . We have assistance on the ground that we have . We have assistance on the ground that we are have . We have assistance on the ground that we are delivering. I ground that we are delivering. We do not have enough. We do not have enough because we are struggling with the impact of commercial airlines over the past couple of months, which have been increasingly reticent to fly in and out of Beirut Airport amongst other airports in the region. We have seen airspace closed due to events elsewhere in the region. We know Above And Beyond the availability of Cargo Capacity flying into beirut, we have prices rising so it is costly to bring assistance in and we need more Assistance And Funding to provide support to the people of lebanon who have been affected and that is why the united nations and partners haveissued the united nations and partners have issued a call for 426 Million in funding to support the response here. Million in funding to support the response here. Because we do not know the response here. Because we do not know how the response here. Because we do not know how long the response here. Because we do not know how long all the response here. Because we do not know how long all of do not know how long all of this will continue. Just a final thought on a human level. Some of your colleagues put on Social Media what it is physically like to be in that city when some of these huge bombs go off like they did last night. Just describe what it is like. J night. Just describe what it is like. ,. , night. Just describe what it is like. , night. Just describe what it is like. A, a, like. I am in a way lucky because like. I am in a way lucky because i like. I am in a way lucky because i have like. I am in a way lucky because i have a like. I am in a way lucky because i have a house| like. I am in a way lucky because i have a house with a roof over my head and i can still stay in my house while this is going on around us. Extrapolating out with the displaced who are sometimes on the streets, sheltering in parts of the city are feeling, when we have these huge Air Strikes that are taking place not just once, strikes that are taking Place Notjust once, twice, there were multiple strikes last night. One of them was in the centre of the city. About 500 metres away from where i am sitting. It is terrifying. It is terrifying for the people of lebanon, for the humanitarian workers trying to bring them assistance, but also struggling with their own effect of the crisis. Theirfamilies with their own effect of the crisis. Their families are with them and we have lost people in them and we have lost people in the un and ngos say thank you for recognising that and thank you for allowing me the opportunity to bring some of that perspective to you. We are crateful that perspective to you. We are grateful for that perspective to you. We are grateful for your that perspective to you. We are grateful for your time. That perspective to you. We are grateful for your time. Thank i gratefulfor your time. Thank you. In describing what it is like to be in the city. We can turn to the calculations that are being made by israel in response to what we saw on tuesday night. Israels Prime Minister, benjamin netanyhu, has held a Security Meeting to discuss exactly how his country will respond to the wave of ballistic missiles iran launched on tuesday. Yesterday, President Biden said he was against israel targeting irans nuclear facilities. David albright is an american physicist, Weapons Expert, and the founder of the Institute For Science And International Security in washington. He told me how close iran was to having a Nuclear Weapon. I think, dangerously close. I mean, iran has shown that it can make Weapon Grade Uranium in sufficient quantities for a Nuclear Weapon within days, and accumulate enough for several Nuclear Weapons in a month. And so that part is settled. Now, thats the raw ingredients for a Nuclear Weapon. But theyve worked on Nuclear Weapons a lot in the past and so they know how to do it. And so my own estimate is in about six months, they could put together a crude nuclear explosive device that could test underground. They could declare themselves a nuclear power. I dont think it would be deliverable by missile. I think that would take longer. But nonetheless, if you look at other countries and what theyve done, like pakistan, india, north korea, they didnt wait till they had a Missile Deliverable nuclear warhead to declare themselves nuclear powers and to do it in a credible manner in the sense that the international community accepted it. So if israel were to try to hit those facilities, how easy or difficult would that be . I think its certainly a difficult problem. And its not like when israel attacked the syrian reactor, 2007. Its a much more diffuse programme involving enrichment of uranium. Theres stocks of it of 60 enriched uranium, which is just a slight step from weapon grade. Theres lots of centrifuges. Its notjust one reactor. So its a difficult problem. But over two years ago, the israelis were pretty clear that they said we needed two years to plan an attack on irans nuclear facility. So those two years are up. And so theyve been thinking through how to do this. And i think they can do things that will surprise us. Who would have thought theyd put Explosive Material in pagers and just decimate hezbollahs mid level operatives . So i think the israelis have been thinking about this, and its something that they probably could do, and they could do quite a bit of damage to the iranian nuclear programme. Could they do it on their own, israel . I think thats been their plan. They want us assistance. But from what i understood in discussions when this was being discussed over two years ago, was they plan to do it alone, and they would look to the united states, obviously, for help rearming, for intelligence, you know, help against any iranian retaliation. But i think the idea was they would they would be self sufficient in order to attack. A final question, because i heard you in a Radio Interview say, actually, weve reached a point that perhaps the pressure from both sides makes this more likely. Just elaborate on that point. Why do you think weve actually got to a moment where something thats been talked about for a very long time could be potentially about to happen . I think iran did believe that its Ring Of Fire was a deterrent keeping israel from attacking or going beyond certain limits in the region, and thats now gone. Iran has also said that any attack will overwhelm your defences with missiles and really cause widespread damage. That hasnt happened. Israel responded very, very well in showing that deterrent doesnt exist. And so i think iran may be thinking, and certainly in the iranian discussions that you hear in the Social Media and the media, they feel that a Nuclear Weapon would provide the deterrent that would keep israel from attacking. So i think the chance of them doing that now is increased. On the other hand, israel is looking at a country that made big threats about eliminating them and attacking them aggressively if they attacked if israel attacked iran. And those threats dont seem that big. And so iran is vulnerable now and kind of reeling from Everything Israel has done in the last couple of months. And so i think israel would feel incentivised to attack now or in this time period. That was the Weapons Expert david albright. Around the world and across the uk. This is bbc news. You are watching bbc news. We will keep an eye on what is happening in the middle east. We will keep you up to date. There is also the live page. Head there and there are continuous updates. But now we can turn to another fascinating story. About 100,000 newborn babies in england are being tested for genetic diseases as part of a new study aiming to improve diagnosis and treatment. More than 200 rare diseases will be detected in the screening process, meaning babies can be treated and, in some cases, cured at the earliest possible age. Lets speak to Dr Sophia Varadkarfrom great ormond street hospital. She is a consultant paediatric neurologist and was involved in setting up this study. Welcome. This is said to be ground breaking. Tell me more about what you have done. It is an exciting about what you have done. Ut 3 an exciting opportunity to improve the care of babies and children with rare diseases. What is special is the study is a collaboration between genomics england, Maternity Hospitals and the service. Helping to set up pathways so when a family is told their baby has a condition suspected, we can quickly get them linked in with specialist paediatric Childrens Hospital teams to see the baby quickly and confirm the diagnosis is correct and start treatment as soon as possible. Correct and start treatment as soon as possible. Give an idea ofthe soon as possible. Give an idea of the types soon as possible. Give an idea of the types of soon as possible. Give an idea of the types of diseases. Soon as possible. Give an idea of the types of diseases. Overj of the types of diseases. Over 200 diseases. Of the types of diseases. Over 200 diseases. A of the types of diseases. Over 200 diseases. A couple of the types of diseases. Over 200 diseases. A couple of 200 diseases. A couple of examples. There are rare diseases where babies do not Clot Blood properly and they lack Clotting Factors and as newborns, they can have lead in the brain that can cause long Term Damage so if you start treatment soon you can prevent that. Another is babies with rare causes of a drop in Blood Sugar that can cause Brain Damage and seizures. Another area is spinal muscular atrophy, children who would die young or never be able to walk. Now if we get treatment early they can live and we will see some of them walking and having the chance of a really good life. It the chance of a really good life. ,. , life. It is incredible. If it turns out life. It is incredible. If it turns out to life. It is incredible. If it turns out to be life. It is incredible. If it turns out to be what life. It is incredible. If it| turns out to be what you describe. Currently, without this, tell me what happens, what you are hoping to map out in the coming years and what currently is happening. Currently is happening. When arents currently is happening. When parents begin currently is happening. When parents begin to currently is happening. When parents begin to suspect parents begin to suspect something is wrong and parents are good at that, they realise something is wrong, then they look for answers and see the gp, paediatricians, and with good care for rare diseases, it can take time to find the answer. We sometimes call it the diagnostic odyssey. Months of years when everyone knows there must be a reason but we cannot find it, so scans, tests, and in The End of diagnosis that hopefully will get treatment. The idea here is we make the diagnosis before the child begins to show something is wrong. Get the treatment early, change the course of that disease, treat it and in some instances take away the effects completely. I5 away the effects completely. Is this only for diseases that have treatments and, longer term, are you hoping potentially this becomes a Routine Test . Routine test . Yes. At the moment. Routine test . Yes. At the moment, it Routine Test . Yes. At the moment, it is Routine Test . Yes. At the moment, it is selected. Routine test . Yes. At the l moment, it is selected for Routine Test . Yes. At the moment, it is selected for over 200 diseases which have a treatment available for that baby in the nhs. In the future, we see advances being that there are more treatments available for rare diseases. So if this study works out well, it could be offered to every baby, just like they currently get things. Baby, just like they currently get things baby, just like they currently iet thin. S. ,. ,. , ~ get things. Fascinating talking to ou. Get things. Fascinating Talking To You we get things. Fascinating Talking To You. We spend get things. Fascinating Talking To You. We spend so get things. Fascinating Talking To You. We spend so much get things. Fascinating talking i to you. We spend so much time looking at depressing, distressing images and stories. This is not one of those, this is a story that brings hope. Thank you for coming on the programme and explaining it so clearly. A pleasure. We will have the latest Business News in terms of the middle east. We had a spike in Oil Prices. Good afternoon. It was an absolutely glorious start to the day, and most of us will keep sunny spells into the afternoon, but it came at a price. It was a chilly start, the coldest Autumn Morning so far in braemar in scotland, and we had some patchy Mist And Fog as well. As you get when High Pressure dominates in autumn. And that High Pressure is going to stay with us for the rest of the day and into tomorrow. But we will start to see a change developing as we go through the latter stages of friday into the start of the weekend. Theres more wet and possibly windy weather to come as well. So enjoy the sunshine for the remainder of the afternoon. Sunny spells, a little bit of fair Weather Cloud developing into the afternoon, and perhaps the breeze picking up and a few isolated showers into western scotland. But on the whole, temperatures will peak at around 13 to 17 degrees pretty much where they should be for this time of year. As we go through the evening, the winds will continue to strengthen further and this Weather Front will bring some Showery Rain Into Northern Ireland and northwest scotland. Clearer skies across england and wales will mean temperatures once again into single figures. And because of all the rain that we had in september, the ground is pretty moist so we could see further Mist And Fog forming. The high is drifting slowly eastwards and that means that these Weather Fronts will start to push in from the atlantic, but they are going to make slow progress. So on friday, the Showery Rain really sitting across western scotland, Northern Ireland. We might see more cloud developing through the isle of Man And West wales, but on the whole, dry and quiet elsewhere and once again, temperatures peaking into the mid to high teens in places. Now, as we move out of friday into saturday, the next front will start to move in. Again, a slow process being blocked by that High Pressure. But some of the rain will start to turn quite heavy across Northern Ireland and northwest scotland, and the winds will strengthen too. Elsewhere, we should cling on to some sunshine for the bulk of saturday, maybe some rain pushing into Cornwall And Southwest wales by The End of the day. That Frontal System will continue to sweep its way steadily eastwards overnight, so a spell of Heavy Rain and stronger winds clearing across the country. That will linger first thing on sunday and even once it clears, it is going to leave quite a showery story for the second half of the weekend. Oil markets on edge the price of crude jumps on reported comments by President Biden about strikes on Irans Oil industry also coming up a bonus for Uk Borrowers . The governor of the Bank Of England says they could be � more aggressive on Interest Rate cuts if inflation stays under control. Plus open wallets for open ai. Investors pile into the firm behind chatgpt, valuing it at 157 billion, more than banking giant Goldman Sachs plus, the worlds richest Man Versus Wall streets watchdog. Elon musk is due before the sec over his takeover of twitter. But, after his no show last month, will he even turn up . Welcome to business today. We start with the price of oil because crude markets have remained on edge this thursday over concerns about an Escalation of the conflict in middle east. The region supplies around a third of the worlds oil. In the last hour, prices have spiked after President Biden said the us is having discussions with israel about striking Irans Oil industry. Lets just show you how one of the main benchmarks brent crude is trading now. Just above 75 a barrel. Traders though are balancing two things the risk to Oil Supply from the conflict and the demand for oil amid a weakening us economy and a slump in china. Oil expert David Fyfe explained earlier. In terms of iran and the risk to exports