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A 22 year old american who had the worlds first face and hands transplant talks about his surgery, saying he feels grateful for a Second Chance at life. And hundreds of players and officials at the Australian Open Tennis Championship go into isolation after a worker at one of the events� hotels tests positive for the coronavirus. Event� s hotels. A warm welcome to the programme. In myanmar, police have filed criminal charges against the civilian leaders who were deposed in a military this week. There� s been no word on the whereabouts of either Aung San Suu Kyi, or deposed president win myint, since monday. The United Nations said the charges just compounded the undermining of the rule of law in myanmar, and the democratic process, and they called for the Immediate Release of the leaders. For a second day , protesters banged pots and sounded car horns in the country� s largest city. Our reporter Nyein Chan Aye filed this report from yangon. Pots banging people are showing their frustration and anger against the Military Coup. It has taken place on monday. This is the second night in a row people in general have been banging pots and pans and using their car horns in protest against the Military Coup that took place on monday. Essentially, what people here are saying is they don� t want to live or work under the military any more. Singing translation we only respect our elected president ,. And no one else. If the president wanted the military to take over, then, we would have accepted that, but this coup is not fair so we� re expressing our feelings in a peaceful way. We� re the voice of the little people. Translation | witnessedl the coups in 1962 and 1988. We know about what happens under military takeovers, so we have to do this. If we take to the streets, they will shoot us dead. Under these circumstances, i support this kind of protest. We want the elected leaders back. Translation people dont accept the coup. J thats why we want to drive them out by doing this. Pots banging singing on the other hand, the military is taking total control of the country. The military has installed an Ii Memberjunta which they say will rule under a state of emergency. Singing the people of yangon have come out here again in less numbers than yesterday to say they want their vote and voice to be heard. Singing Nyein Chan Aye, bbc news, yangon. Manny maung is a researcher with Human Rights Watch and has worked closely with the rohingyas in bangladesh and in myanmar, shejoins me live from sydney. Thank you for being on the programme. Tell us what you are hearing from people in myanmar about this extraordinary week. Thanks, sally. It� s hard not to get a bit emotional seeing and hearing that reportjust now. The situation is that it is quiet but tense. Everyone woke up quiet but tense. Everyone woke up this morning to the news that facebook actually has been blocked, as has messenger. There are unverified reports that perhaps this will last another 72 hours. But beyond that we are not sure. People are finding ways to communicate and get around that barrier. They are using other services orapp they are using other services or app that we can rely on. But ultimately the phone lines have been patchy, the internet has been patchy, the internet has been throttled at various points and, ironically, while the rest of the country goes into a bit of a shut down or a blackout, rhakine state, the internet has been lifted. figs blackout, rhakine state, the internet has been lifted. As we saw in that internet has been lifted. As we saw in that report, internet has been lifted. As we saw in that report, people internet has been lifted. As we saw in that report, people are | saw in that report, people are peacefully protesting to a degree. Is there a concern about what the military might do if the protests continue . Yeah. And we are definitely looking at this with deep concern. The pots and pans, traditionally as a way of making enough noise to drive out the ghosts and the bad spirits in the home. I think this is one really symbolic move of civil disobedience. If people take to the streets there is concern the military has very, very short patients with dissent and they will crackdown, as they have in previous years, specifically in 1988 and in 2007. We don� t want a repeat of this. People have a right to protest the fact that their elected leaders have been taken down by a, you know, right now a constitutional coup stop by the Un Security Council after its meeting, has called for the military in myanmar to step down and allow for democracy to resume. However, without china� s support what difference do you think that will make . I think right now the key is that governments really need to seek immunity and condemn what is going on. They need to go further put in place these measures and act on what their words are saying and thatis what their words are saying and that is to impose targeted tax and is on the military who are responsible and the architects behind this coup and the crimes against humanity that have been committed against so many of the ethnic minority people of myanmar, including the rohingya. Mil myanmar, including the rohingya myanmar, including the rohin a. � , rohingya. All right, manny mauna rohingya. All right, manny maung from rohingya. All right, manny maung from human rohingya. All right, manny maung from human rightsj rohingya. All right, manny maung from Human Rights Watch, thank you forjoining us. There is much more detail on our website on that story. A new study is being launched in the uk to determine whether using different vaccines for the first and second dose helps the body develop better defences against covid. The current rollout ofjabs won� t be altered until clear results have emerged. Our health correspondent, dominic hughes, has more details. With more than 10 Million People now having had their firstjobs people now having had their first jobs across the people now having had their firstjobs across the uk, the Vaccination Rollout is well under way. Vaccination rollout is well underway. But Vaccination Rollout is well under way. But could mixing doses of the Oxford Astrazeneca and Pfizer Biontech vaccines for even more chances of defence developing defences against the virus . That is what is behind a new trial started today, it will involve 820 volunteers, none of whom have yet had the vaccine. All will be aged 50 or older, part of the group to be vaccinated in priority way. The trial will run initially at eight sites across england. Researchers believe there are good reasons to think it may work. For example, exactly this process was used in the fight against ebola. Introducing flex ability in the Vaccination Programme could also help, should there be disruption to Vaccination Supplies and it may be of huge benefit to developing countries who have yet to get Vaccination Programmes up and running. The first results should be known by the early summer. Dominic hughes, bbc news. Afghanistan� s stalled Peace Process is facing the � high probability of failure�. That� s the stark warning coming from the eu� s commissioner for Crisis Management, who� s visiting the country. In addition to that a bipartisan report to the us congress has strongly urged President Biden to delay a Trump Administration plan to pull all us forces out of afghanistan by1 may. Let� s get more on this from joshua kastenberg, a professor of law at the university of new mexico. He was also a lawyer and judge in the us air force, and joins me live from albuquerque. Thank you very much indeed for being on the programme. Would you agree with the word coming from the eu� s commissionerfor Crisis Management that its Peace Process is only brink of collapse . Collapse . Visible, thank you for having collapse . Visible, thank you for having me collapse . Visible, thank you for having me on collapse . Visible, thank you for having me on this collapse . Visible, thank you i for having me on this morning, and yes, i do agree that afghanistan is sitting on a precipice first of all. And if the Allied Forces pull out and leave the government unprotected at this point there is a very strong chance the country will devolve into a civil war, complete with human atrocity. Civilwar, complete with human atroci. , atrocity. Reports suggest the taliban is just atrocity. Reports suggest the taliban is just waiting atrocity. Reports suggest the taliban is just waiting for atrocity. Reports suggest the taliban is just waiting for the | taliban is just waiting for the withdrawal of us troops before it makes a huge move, as it were, to try to take control. What pressure, talk through politics in the United States and the pressure on the Biden Administration to make a decision and what decision are they likely to make . figs decision and what decision are they likely to make . They likely to make . As you know, they likely to make . As you know. The they likely to make . As you know, the united they likely to make . As you know, the United States they likely to make . As you | know, the United States has had, we have had armed forces in afghanistan and in the region, for that matter, for a very long period of time. It� s costly and there is a strong feeling in the country that at some point in the very near future the last of the troops, the 2500 need to come home. Having said that, as you said there is a bipartisan study that has been resented to the congress and to the Biden Administration which indicates now was not the time to bring forces home. In fact, they recommend increasing the number of united� s forces to a500 at this point. United states forces. The National Security advisor to the present, the pentagon� s you is that president trump� s agreement with the taliban was too soon but the taliban has not abided by the agreements and that human rights, particularly the rights of women and children that we all have an obligation to hold are most at risk president. The pressure on the Biden Administration is more to stay from a strategic, long term view of seeking stability and maintaining our commitment to human rights than it is to leave right away. Mil it is to leave right away. All ri. Ht, it is to leave right away. All right. Thank it is to leave right away. All right, thank you very much indeed forjoining us on the programme, professorjoshua programme, professor joshua kastenberg. Programme, Professorjoshua Kastenberg Stay with us on bbc news. Still to come. The first Tennis Grand Slam of the year plan to start as normal, despite hundreds of players and coaches having to isolate because of covid 19. This is the moment that millions in iran had been waiting for. After his long years in exile, the first hesitant steps of Ayatollah Khomeini on iranian soil. South africa� s white government has offered its black opponents concessions unparalleled in the history of apartheid. And the anc leader, nelson mandela, is to be set free unconditionally. Three, two, one. A countdown to a critical moment. The worlds most powerful rocket ignited all 27 of its engines at once. And apart from its power, its this recycling of the rocket, l slashing the cost of a launch, l that makes this a breakthrough in the business| of space travel. Two americans have become the first humans to walk in space without any lifeline to their spaceship. One of them called it a piece of cake. Thousands of people have given the yachtswoman Ellen Macarthur a spectacular homecoming in the cornish port of falmouth after she smashed the world record for sailing solo Around The World non stop. This is bbc news, the latest headlines protests continue in myanmar as the un calls for the release of leader Aung San Suu Kyi who has been charged by Police Following monday� s Military Coup. And scientists try to find out if using different covid 19 vaccines for the first and second dose may help the body develop better defences. Authorities in south korea have pledged to improve conditions for the country� s 200,000 Migrant Workers after a woman from cambodia was found dead living in a greenhouse in sub zero conditions. Her death is the latest in a series of Human Rights Investigations involving Migrant Workers in the country, most of whom come from southeast asia. Laura bicker reports from seoul. We� re being led through a maze of plastic covered farmland to discover a network of hidden workers. Campaigners here call them modern day slaves. Migrant workers don� t just toil Night And Day in these fields, they must live here too. Inside his shipping container, this worker tells us he came here to provide for his family in cambodia. Endurance for a salary, for money. Like thousands of other legal Migrant Workers, he� s tied to a contract. Translation the hardest thing for workers is that there� s absolutely no freedom of movement, and the workers are bound entirely to the owners. A complete master servant relationship. Nearby, we find a group of young women living in similar conditions. This is their bathroom. About three people will shower, wash, cook in here. It� s like a Container Facility but this is basically where they shower. So this is a bucket and water. For this room, she pays the farmer 150 a month to live here. As well of course, she works eight or nine hours a day. We are told it can be much worse for undocumented workers. But there� s hope that south koreans are finally beginning to understand the hidden cost of their food supply. In the south at a seaweed farm, we find apo. After escaping a cruel contract with only one day off a year, he raised his case with leading politicians. Translation | want to tell. Korean employers that workers need rest and off days. When workers work a lot, the pay should be a lot too. I want to tell other Migrant Workers that we need to be strong if we want to be successful. We shouldn� t give up. We need to face these challenges head on. The Labour Ministry told us they� re already working to reform the so called slave contract, and are investigating all forms of housing. They say they are committed to helping Migrant Workers. With south korea� s population in sharp decline, there� s finally a realisation that not only does this country need these workers, they also need to treat them better. Laura bicker, bbc news seoul. Time now for the latest sports news. Hello i� m Chetan Pathak with your thursday sport briefing. We start in australia where between 500 and 600 tennis players, officials and support staff are in isolation after a worker at one of the Quarantine Hotels tested positive for coronavirus. Play was cancelled on thursday at all six warm up events taking place at melbourne park. Tennis australia says the first glam slam of the year will start on monday as planned though. And the draw takes place shortly. Manchester city have re established a three point lead in the English Premier League after winning 2 0 at burnley. Gabrieljesus and Raheem Sterling scored the goals as city made it nine league wins in a row, and 13 in all competitions. That� s a new club record. It was not about how many games you have two win or types of games of this kind of thing. For the statistics, it is nice to open full pages, that� s ok. But the fact is, what� s next . Try to win and this is the only way we can do it. We have done it in the past and made 18 games in a row, 1a games in a row. There is always the next ones. Jurgen klopp� s liverpool suffered a second successive home defeat this time brighton were the side getting the shock win. Steven alzate scored the only goal of the game against the champions. Liverpool are 7 points behind Manchester City who they face on sunday. In spain, barcelona are through to the semi finals of the copa del rey but only after surviving a scare at granada where they had to come from 2 0 down. Antoine griezmann and jordi albai both scored in the last three minutes of the 90, to send the game into extra time. And they were both on target again, along with frankie de jong, as barca won 5 3 to reach the last four. There� s one game in the English Premier League on thursday as tottenham take on chelsea, with both sides seventh and eighth in the table with 33 points each. At the weekend, Thomas Tuchel got his first chelsea win since taking over, a 2 0 victory over burnley, and now comes up against a former chelsea manager injose mourinho, whose success he says he� d like to emulate. Is it isita is it a clash of cultures . I don� t know. I thinkjose mourinho is a winner and i want to implement the same in my teams. We are at the highest level to win games and we will try everything tomorrow to beat them in their stadium. And finally, british sailor pip hare has been on her own for nearly 90 days competing in the Vendee Globe Yacht Race around the globe. It can be a lonely way to spend your birthday, so a bbc local Radio Station decided to tweet Russell Crowe who she� s a big fan of to see if he� d send her a special message. And to his credit, he did. Hgppy happy birthday, pip. I hear you� re sailing around the globe. Notjust this morning i was up govs creek, had a part also admitted to easier. So it is a similarjourney, i would imagine. I� mjust sitting is a similarjourney, i would imagine. I� m just sitting here thinking about the incredible challenge in front of you and how overwhelming it must feel some days. Just keep going. What an amazing feeling you� re going to have when you can say you have claimed the globe. Hgppy you have claimed the globe. Happy birthday, pip. Sale well. Sail. Nice touch. Just a reminder you can follow day one of the second test between pakistan and south africa on the bbc sport website right now. But from me Chetan Pathak and the rest of the sport team, that is your thursday sport briefing. Well done Russell Crowe and thatis well done Russell Crowe and that is definitely a lockdown beard. Don� t you think. Tell me what you think, i am on twitter. As chettan was saying in the sport, the Australian Open will begin as normal despite the announcement that hundreds of players and support staff must self isolate after a Security Guard tested positive with covid. Our correspondent Shaimaa Khalil reports from melbourne. We were expecting big names for Warmup Events here in melbourne park. World women� s number one ash barty, naomi osaka, halep and is a regularand ash barty, naomi osaka, halep and is a regular and the metro and is a regular and the metro and dan evans, brought you to play here today. This is a chance was some more practice out of The Main Event on monday. Bad we needed really for many of the players who were cooped up in quarantine when some positive cases were detected on the planes that brought them here to australia. None of that is happening today. With more than 500 players, officials and coaches now having to isolate after a man who was working in one of the tournament� s Quarantine Hotels tested positive to covid 19. They now have to return a negative test to be able to get back to the competition. Whatever happens with those tests of course will determine how the next few days are going to go for the competition. It is usually frustrating, notjust for competition. It is usually frustrating, not just for the players and officials but also for tennis fans. Players and officials but also fortennis fans. Remember, for tennis fans. Remember, melbourne fortennis fans. Remember, melbourne has been through wannabe well� s longest and harshest lockdown. Many here were quite excited that the Australian Open was going to go ahead, a sign that the city is coming back to life. As it stands, officials tell us that the main tournament is going to go ahead on monday, so they will be watching this very closely. So too of course, will the major Event Organisers Around The World. They will want to know what has worked and what hasn� t here at the Australian Open. Not least the olympic committee. They themselves have been screaming to get the games going in tokyo later this year. So not much happening around me now but on monday, if the tournament goes ahead, up to 30,000 people are expected here at melbourne park. A 22 year old american has had the world� s First Successful face and hands transplant and has been talking about the surgery. Joseph dimeo who suffered 80 per cent burns to his body after a car accident in 2018 said he felt really grateful. Mark lobel has this remarkable story which contains images of the patient� s original injuries. Newjerseyanjoseph dimeo was a fun loving teenager and son, by the 22 year old saw his life turned upside down when, after a night shift, he fell asleep at the wheel. His vehicle exploded his body severely burnt. His parents became his carers. His fingertips were amputated, he lost his lips, ears, and eyelids. Most people with that amount of burns, they don� t survive. He essentially had a 6 chance of identifying someone that would be a proper donor for him. Against the odds, a donor was found in august. Days later, a medical team of over 1a0 in new york replaced bothjoseph� s hands and transplanted his whole face face in a 23 hour procedure the third ever attempt, but the first truly successful one. So we can let you look in a mirror. Big smile. See how everything is starting to move . Isn� t that great . Open your mouth real wide. Five months on, joseph is responding well to his new face and hands. The primary goalfor him was to gain his independence. He� s doing amazingly well. And it� s a testament to him as an individual, his commitment to his therapy, and his willingness to not give up. I can eat breakfast for myself and work out by myself, even on my days off i still work out. Im almost there to normal living again. Itsjust, you know, my goal is to move out of my parents house again. Building up his strength and working out how to pinch, squeeze, blink, and smile again, joseph is waiting to hear back from the donor� s family, who he says he doesn� t really know how to thank for giving him such a precious Second Chance at life. Mark lobel, bbc news. What an incredible story that is. To stay with us, we have so much more to come was not including all of the latest business news, such as ebay which is one of the latest companies to release their earnings. I was even a moment. I will see you. Hello there. Winter is about to ramp up to another gear by the end of this week, certainly into the weekend. It� ll be turning much colder with the risk of some disruptive snow in places. So for the next few days, it� ll gradually be turning colder for all, and we� ll see increasing snow particularly over the hills in the north. Now for thursday, we� ve still got low pressure close by to the uk, it� s the Weather Front across the north bringing further cloud, outbreaks of rain to northern ireland, much of scotland, Northern England too, and here we� ll see further snow over the scottish hills accumulating and drifting in that strong east southeast wind. Further south, after a bright start to the day, we� ll start to see showery bursts of rain moving up from the south. Here, it� ll tend to be fairly mild, 8 10 celsius, but very cold across the north where we have that snow. Through thursday night, it continues with rain and the snow across scotland significant accumulations over the grampians and the highlands, very wet weather with a risk of flooding. Further south, a drier night to come and clear skies, could see some mist and fog across southern england, and again, a big temperature contrast from north to south. Now the snow continues as we head on into friday and saturday significant accumulations have prompted the met office to issue an Amber Warning for this heavy, incessant snow. And also, some very heavy rain for lower levels could cause some localised flooding so a whole host of issues there. Tends to stay dry across the far south east again, 9 10 celsius, much colder further north where it will also be windy with that drifting snow in the hills. Moving on into the weekend, our area of low pressure sinks a bit further southwards, so it means the rain and the hill snow across Scotland Will Drift into parts of Northern England at times too, so a whole wintry mix here could be disruptive. Further south, quite a bit of cloud around with outbreaks of rain, and temperatures dropping generally across the board. Still cold in the north and a little bit colder for much of england and wales, too. As we head on into sunday, the very cold air across the east pushes southwards right across the uk, and it� ll be very windy, so the wind making it feel even colder 2 3 celsius, some snow pushing into northern and eastern areas which could be disruptive. So turning very cold through this weekend for all areas, with the risk of some disruptive snow for some of us. Hello again. I� m sally bundock. We are now bringing you the top business stories. Will washington stop the game . The us Treasury Secretary and financial watchdogs to hold talks on the reddit fuelled amateur trading frenzy. Buy it now investors bid up ebay shares as the online marketplace sees Business Surge during lockdown. The future of music or a threat to it . Mps continue their enquiry on the economics of music streaming. Plus, fouled by covid. More pressure on football� s finances as european broadcast rights take a dive

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