Scipio theres something the venom can now be sent to all of our 3 finances is not limited to being drunk yes. Sometimes its very painful. Sometimes it can make you cry. You cant deal with a threat to human life unless you know its that and that means detection is one of the most important parts of any Health Professionals work but here in east africa many of the most sophisticated diagnostic tools from genetic testing to nuclear simply too expensive im dr javid up to my neck in tanzania was scientists are busy turning local pests into a crack team of disease detectives. Africas giant couch rats have an exceptional sense of smell and a dose on nature which niggers e bay and his colleagues at the charge of piper harnessing to save lives. Look at these rats the huge they even have names so heres this this is more you got a huge rat called mojo and its all ok and this is a specially trained rat yeah trying to do was thinking on it once detecting around a month. Every morning the rats are taken to nearby training fields to practice sniffing out the explosive agent t. N. T. In deactivated land mines. Wars have left many african countries littered with millions of land mines and unexploded bombs. Clearing them is notoriously dangerous slow and expensive. But appropriate here rats work 10 times faster than humans alone to like to set off the mines and will work for peanuts or in this case bananas. In training the rats scratch the ground where they think they swell a mine since 2008 the rats trained here have cleared over 900 football fields worth of heavily mined land in neighboring mozambique that is just the sea ice for when i benefit from q which is making a Significant Impact in the natural fit for the road to show you the office. As theyve done so well at sniffing out mines the rats exceptional noses and now being put to work on one of africas deadliest diseases so you just might never mind going to trying these rats to smell is really in the history hypocrite thats merely to detect some day it is so its a good something new every week sputum samples from 17 tb centers are sterilize for safety then a stream to the papers lab which is the 1st in the world to use rats to diagnose disease and say these are real actual tuberculosis kits and samples from local hospitals yeah this source what im sometimes called looked at from suspected to be patients. All the samples have already been tested in hospital but outdated methods mean many tb cases a mess those that have been confirmed are left in to test the routes accuracy but only one technician in the room knows which is which for all of the bars he knows hes a politician off the positives that he to hand this to pay i dont know the position and the right doesnt know even that out just so thats what we call a proper double blind test no doubt is created to sniff. The technicians want to see whether the rat scratch i have. In the confirmed cases and if they suspect any of this. Sort of love. Was used. So its indicated on the no one positive click followed by 4 followed by food and number or so but not indicator but it was the most polluted from the t. V. Saying so she said suspect so we dont yet know that it could be positive if its the wrong things it is now 10 percent over just one issue yeah wow how long would that have taken microscopist when i was. A single technician 25 something that day by day here 25 some pills a day and disrupted 10 and 10 sound person a minute thats 10 fold 50 fold on you can do the math thats very much for. The rats cartney screen around 800. 00 samples a week and news of their work is sporadic so im going to introduce you to janet janet is a former t. V. Patient. So how do you really want. To conquer some us attorney. Says. You know when looking for one. Lesson in fall sick. Of virginia and they. Need. To fall. Back to near one up on. Every week the routes flag up dozens of samples missed by hospitals which are then retested using a purpose up to date methods so to moderate prepared this smears from this put them someplace else where it indicated why thats the focus is suspect so hes going to stay in this smears so that sort of counter staining. Thats integration process make sure that the only the bacterium itself picks up the color and Everything Else in the background will fade in deep trouble so that when you look at it under a microscope its very obvious so here its a microscope your own oh. So you know we turn the lights off so were in the dog because this is the fluorescent dye and so the bacteria actually glow in the dark so she can have a look here 1st look. Right. Now this is theres a lot that i wouldnt even have to count to miss but 2nd to see that is at least 20300 bacterium and not feel so so thats thats really nice to see the rats have got it right you know our rights i think astrid she she she actually got a suspect case that is actually positive and that would have been missed with the ordinary diagnostic tools that we had in the community so thats brilliant more than 2600 patients were missed where the tb clinics but by the routes and confirmed there. Since 2008 the rats have improved tb detection rates by 30 percent and with 45. 00 new clinics to join the Program Next Year these extraordinary rodents are set to save thousands more lives. Planning coming in pushing. The stump why the same d. N. A. Copland. Living with thomas can make everyday life to close these involuntary muscle movements a fact simply to start writing or even drive a car they could not have the medications can affect but if they dont work an invasive risk to the brain surgery is often the next step im dr elizabeth even in ohio usa to find out about a new procedure they use its not a static and the incision its a jury without. For most of my life 58 year old sonny has suffered with essential tremor logical disorder that causes involuntary muscle movements so. I create abnormal activity deep in the brain causes shaking which is especially noticeable in the hamptons and something that can be extremely disabling and thats very fine fine control and i thought that was the last one i was able to do i cant do that on sunday how long have you had essential travel at. Least since i was. What is it worth to both my hands. Its in my head especially if i do any and to mouth motions i only drink out of a straw and. Going to someones house to eat unless i know the last or well i just i dont do it i just dont do it brushing my teeth its a nightmare ive damaged my gums again tell you how mean. I have scars all over my hands cooking can you show me what your writing is like. Ok. Thats hard work for you isnt it for the transfer the table. Can be very strong. So i can just lay that out where i am as sunny hostin feel when your body is doing something you cant control. To bare. Bones is very painful. Sometimes it can make me cry. Because there are so many things id really like to do and i know i can do but im not allowed to because in my hands. Invasive surgery and radio surgery can be used to target the effect of cells that cause tremors from within the brain but these procedures carry significant risks surgeons and. Scientists at Ohio State University is what the Medical Center are now trying a completely noninvasive technique focus on disorders a new technology that uses the power to focus on being pushed to go through the skull and meet at a Central Point within the brain and the energy from all these wasnt being minds together it is powerful enough to all of a small and criticize vision of the brain its a bit like when you use a magnifying glass to concentrate light rays to burn something will stop fire yeah absolutely so what are the advantages of this procedure over the current procedures for such a minute grandparents are all focused on just how are they is it being given on a razor to show without opening their skull patients are overweight and you can look at their specific tremor while they are drawing objects or writing an immediate feedback that you get is a key part of this procedure that allows us to be accurate while the patient is still on the table so excited that i do indeed is for sure. Sonny is just the 7th person to undergo this new procedure at the what the Medical Center as part of a clinical trial. Ok so sun is pretty much all set to sort of go into the machine because during the filming back but we can so again and this is kind of the control sense that this is the point without question will be manipulating the controls to to get the fact he wants. To see the reconstruction of the sun is. Known as long. As you go to school you can see this is a former school a lot of the ocean views. And much room for these folks in u. He brings home for you. This is the part of the brain i think i can be part of and you can see the ultrasound maser coming in from different elements in the largest morning brain science. And now the next step is to stop day the treatment step by step to see how much energy needs to to try to travel ok the focus. Was the. Same start. Dr krishna treat sonny with 14 sessions of ultrasonic and itching known as sonic ations which will burn the fact cells and have brain each sunday cation loss around 10 to 15 seconds you know anything at all. Hard to pick. Up the aca will test the movement and right to monitor an improvement and determine how well the treatment is. So these are spiral drawings on the line for us her rights to see about her and i will give her some short sighted patients in a safe us change a choice that takes. 30. 2 minutes for 10 seconds. This is number 6 thats highest character searches their interest should actually not rush through this exciting stuff that great this is the big one of the she said this is that they want to get the full amount of calls a vision thing we want. To do not. See what. Shes done that says. To see how can i just think pointed straight last sunday keisha. And its got steady. But. Thats the big grand very big thing oh my where are these experts tell you theres smoke theres fire plant its recalled 0 so this treatment has been extremely today. On. C. B. S. To fix all. That stuff. Was money well the more the more you. Hear. Kill. Ready ready the following day i visit sunny to find out how shes getting on. Getting on him my knee is pretty. Amazing. Pretty good pretty good. Shakes solid as i look yes my goodness me that this is the 2030 years to retrain your hands and actually do stuff you want to tear system i do it kind of have to talk to it semi yesterday how we feel about the whole procedure you know where the thing. I was when i was in it was really hard not to like star jones. In that thing i was like oh. Yeah i was by this like all cricut its work its going to affect practically every movement they make it everything absolutely everything. The team hope to get Us Government approval for this procedure by the end of the year which means that it will become available to other patients outside of the trial its extraordinary to witness the Immediate Impact this has had on sonny and trying to make it through commercial you what you do with us to get. Very good. And i. Think. Starvation. Pretty good dogs at that. Circle do you expect to do that if. Ive been hoping for you then. I guess sometimes hope come true. Most of us view venomous animals such as snakes scorpions and spiders as creatures to avoid this scientists believe that their toxic venom could be a vast untapped resource for the development of lifesaving drugs im dr just placing and im here in the south of france on the hunt for some extraordinary animals with the potential to save lives the next project is a collaboration of venom experts from across europe i mean to find new drugs capable of treating conditions such as cancer diabetes and cardiovascular disease. This is my way to meet here is one of the lead scientists involved with an enormous project and him and his team hunting for a school kid and say. Yeah nice to meet good to meet you thank you for having me here its crazy well yeah isnt it so we should go search your little girl field but. Thats a big loss so is it literally case of just picking up rocks and absolutely yeah in the area trying to solve. The problem well among the laws yeah right click on them. Will. Send this assume thats the way it is. This is a member of the family of scorpions does our little to. You know. Thousands of people every year. In morocco in tunisia. In mexico. May be nervous its not going to jump your legs angry. Flame to me what exactly is involved with the project. The enemy is a large scale project aiming at discovery of new drugs instead of using for example Medicinal Plants to look at new yorks were using because they hold such a high potential and the such a large number of. This seems slightly in congress the venom thats designed to. Kill you could potentially be the source of life saving drugs but then again a poisonous plant also has the same properties and if you extract these compounds one of those compounds given that the right those age can actually cure you. Of the we should we should start lifting rocks if you go. To. The talks of proteins or peptides within venom target and interact with specific cell receptors within the body affecting the vital functions of the heart nervous system blood or other tissues. Its the targeted nature of these toxins that gives an issue to potential for the development of drugs which have highly specific and effective therapeutic action. Toss to find a scorpion omar and off again its experts who have already found several themselves. For my pride i have to find one. For one. Needs me thats it. Exactly. Thats it were really. Going to. Score your 1st call. The estimates we have currently are about 40000000 money curious altogether from from all the other side email so we know about 3 to 4000 only basically we are key hunters were looking were looking to look at least the long yeah interests you can find the keys to the lock on the cancer cell for example so century could be essential provided there is a suitable law for reception these creatures hold an immense potential for Drug Discovery the venom makes project has laboratories in france denmark spain belgium and portugal and he aims to source the venom of over 500. 00 species of animals including snakes jellyfish and cones nouns one appears partners in france is an expert in the breeding of large spiders. After you think. Wow. Its hard hello harm us rocky im also nice to me. Im surrounded by spiders youre surrounded yeah im feeling very comfortable but. Mainly a little bit in front to the time he just was a day we should militias budgeting spiders sometimes called. Abilities pointers and here you are breeding. Spiders as well as not just to find those. To provide for the rituals for and you know them here yes of course why school is the society with the project because hes got a unique facility you probably have no more than 4 or 5 people in the world who can actually breed spider is a military studying the diversity of the known world will allow us to uncover. A diversity of more each will suite Different Properties that i ask can we can we see some of them. This one is a huge one you see if you try to really come steel hungry surats. These this isnt on the quay looking. Rule. Its a very large spot yeah very nice also quite put to the jury goes to the shes front. And can we see you know king some of the spiders as good as. It will. Be to sleep. C. E. O. Apply and come dockside straight to the lungs absolutely. You can see slow down and shes. In the ozone nose now. Called from. When they put some interesting causes the muscle to to trench x. On the x. Course the. Yes. Your wrist by your spine and sapir this sample of venom can now be sent to your laboratory finances is not limited to being dr just. Jumps up to its lets step into the thank you so here the facility on his or her the are some of the sculptures we collected previously were going to extract some venom from this. Options because we need for the project both venom and venom glands but if you want to try you can have a go at milking ok yes so i will install the scorpion in a holder and then world stimulate it with a bit of a trickle charge. I will 1st ground the scorpion gently we going to. Put in here and you got to hold this yummy stuff i think i love you giving it giving out shocks my linux recall current can you see the venom drop yeah ok well thats enough to run through i know that it is absolutely absolutely. Perfect. Once melt the team separate the venom into its constituent peptides which will then be added to a bank of molecules ready for an ounce of. This project has the same excitement in the fact that it is as you say this kind of leap into the unknown with such a strong chance youll find something of interest youre exploring something thats never been explored like going to other planets as a scientists intellectually extremely exciting and the signal reason for excitement is that you hope that you can make a difference one day and maybe all of all this work to get a cure for something thats 2 reasons for being so n. T. S. B. From cutting Edge Medical Technology toxic venom could be a vast Resource Development problem lifesaving drugs to advances in the most difficult regions of the world. Governments come to thank you. For you. Every. Innovative solution to Global Health care problems to make a difference maybe all the oldies were good it sure was still the cure on aljazeera. Business updates brought to you by Qatar Airways going places together. Business updates brought to you by Qatar Airways going places together. This is aljazeera. The new. Challenge to the one country 2 systems policy those strong words coming from china over the storming of hong kong. Also frances president calls on iran to reduce. Them to save the 2050 new deal and deep divisions in. The new European Parliament is meeting for the 1st time