<p style="text-align:start">A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk — 451 in all — through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet. The research explored the genomes of nearly 950,000 men, including major increases in representation among men from racial and ethnic groups that have often been left out of such research. The study identified 187 new genetic variants linked to prostate cancer, revising what is known about genetic risk for the disease. With these findings, the researchers improved a system they developed for measuring genetic risk so that it was more effective in predicting who would or wouldn’t develop prostate cancer — even distinguishing between the likelihood of aggressive and less-serious cases among men of African descent.</p>