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Hemodynamic assessment did not improve guidance for complete revascularization in multivessel stenting for patients with ST-segment elevation MI (STEMI), according to the FLOWER-MI trial.
Fractional flow reserve (FFR) was no better than angiography at guiding percutaneous coronary intervention (PCI) on nonculprit lesions in terms of 1-year clinical outcomes among more than 1,000 study participants, reported Etienne Puymirat, of the European Hospital of Georges Pompidou in Paris.
By then, the combined rate of all-cause mortality, MI, or unplanned hospitalization leading to urgent revascularization was similar between patients randomized to FFR or angiographic guidance (5.5% vs 4.2%, HR 1.32, 95% CI 0.78-2.23). There were no differences in individual endpoint components either, Puymirat said at the American College of Cardiology (ACC) virtual meeting. FLOWER-MI results were simultaneously published in the
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