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Bidirectional impact of cardiovascular disease, cancer in Blacks focus of new AHA center

Credit: Kim Ratliff, Augusta University Cardiovascular disease and cancer, the nation s top two killers, share common ground like obesity and chronic inflammation, as well as a disproportionate impact on Black Americans. A new American Heart Association-funded center at the Medical College of Georgia is working to better understand the bidirectional dynamic, including how to intervene when, for example, cancer treatment itself results in heart problems. MCG, the state s public medical school, is one of four centers nationally funded by the $11 million AHA Strategically Focused Research Network on disparities in cardio-oncology, which also includes Boston University School of Medicine, the Medical College of Wisconsin and the University of Pennsylvania.

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases An internal transporter that enables us to use the copper we consume in foods like shellfish and nuts to enable a host of vital body functions also has the essential role of protecting the receptor that enables us to grow new blood vessels when ours become diseased, Medical College of Georgia scientists report. The findings published in the journal Nature Communications point toward the copper transporter ATP7A as a potential new therapeutic target in treating cardiovascular diseases like heart attack, peripheral artery disease and stroke. Our paper is talking about a newly discovered function of ATP7A, says Dr. Masuko Ushio-Fukai, vascular biologist in MCG s Vascular Biology Center. Our paper shows that ATP7A directly binds to the receptor for vascular endothelial growth factor, called VEGFR2, to stabilize it, to regulate the receptor itself, she says of the receptor that enab

Obesity, High-salt Diet Ups Cardiac Issues

Obesity, High-salt Diet Ups Cardiac Issues by Angela Mohan on  April 30, 2021 at 5:24 PM Obesity and a high-salt diet can increase the risk of cardiovascular disorders. We see younger and younger women having cardiovascular disease and the question is: What is the cause? says Dr. Eric Belin de Chantemele, physiologist in the Vascular Biology Center and Department of Medicine at the Medical College of Georgia at Augusta University. We think the fact that females are more salt sensitive and more sensitive to obesity are among the reasons they have lost the natural protection youth and estrogen are thought to provide. First reduce your consumption of salt, a message the American Heart Association has been pushing for years, which should also result in a reduction in your intake of highly processed, high-calorie food and drink. , he says.

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