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(0) NEW YORK, NY / ACCESSWIRE / April 1, 2021 / Kadmon Holdings, Inc. (NASDAQ:KDMN) today announced that the first patient has been dosed in an open-label Phase 2 clinical trial of belumosudil, the Company s ROCK2 inhibitor, in patients with diffuse cutaneous systemic sclerosis (dcSSc), a chronic immune disorder characterized by fibrosis of the skin and internal organs. The Phase 2 study (KD025-215) will enroll up to 15 adults with dcSSc who will receive orally administered belumosudil 200 mg twice daily (BID). The primary endpoint is the Combined Response Index for Systemic Sclerosis (CRISS) score. The Company plans to present initial data from this study by year-end 2021. In addition to the KD025-215 trial, an ongoing, double-blind, placebo-controlled Phase 2 clinical trial of belumosudil (KD025-209) is currently enrolling 60 adults with dcSSc. Patients are randomized to receive belumosudil 200 mg once daily (QD), belumosudil 200 mg BID or placebo. ....
Small changes made with gene editing cause severe deformities in plants LATEST VIDEOS Small changes made with gene editing cause severe deformities in plants Details New study points to unintended effects of gene editing in plants and potential negative effects on ecosystems Gene editing causes drastic unwanted effects in gene-edited plants including severe deformities, a new scientific publication in the journal Environmental Sciences Europe shows. This is the case even when the changes are intended by the gene editor to be small tweaks to existing genes rather than, for example, the introduction of new genetic material. More broadly, the study provides an overview of the negative effects on ecosystems that can result from the release of gene-edited plants. These unintended effects result from the intended changes induced by genome editing, which can affect various metabolic processes in the plants. ....
Minerco, Inc.: Minerco Acquires $2.5M of Revenue from White Label CBD Company, WLCCO Inc Minerco completes purchase of WLCCO Inc and increases psilocybin production capacity Oakland, California (Newsfile Corp. - March 14, 2021) - Minerco (OTC Pink: MINE) announced today that they have acquired WLCCO Inc, a white label CBD company that generates approximately $2.5 million in annual revenue. This strategic purchase includes crucial equipment, increasing microdosed psilocybin tablet production capacity by 1 million units daily. In markets where psilocybin is not legal, Minerco will manufacture unleaded medical mushrooms including Chaga and Lion Mane as legal alternatives. Minerco leadership announced the company s four critical goals at the Sankofa Shareholder and Vision Summit held on January 24, 2021: ....
SunStar + March 16, 2021 RESPONSIBLE for providing Cebu City with plenty of its much-loved locally crafted tunes, record label 22 Tango Records announced its rebranding last month: The company now refers to itself as 22 Tango Music Group. 22 Tango Music Group is a multi-faceted music company which includes services like music distribution and publishing, artist management, events, recording arts and production, and music education. “We’ve always been focused on growth both for the music industry and our company. So when the company was about to celebrate its 10 years in the business in 2020, we thought it was a good time to make the expansion official by changing the brand name and to officially register as a corporation,” said 22 Tango Music Group chief executive officer and co-founder Cattski Espina. ....