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Trophoblast motility in a gelatin hydrogel
New Rochelle, NY, December 18, 2020 Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall. A new multidimensional model of trophoblast motility that utilizes a functionalized hydrogel is described in the peer-reviewed journal
Tissue Engineering, Part A. Click here to read the full-text article free on the
Tissue Engineering website through January 18, 2020.
This valuable new tool, based on a methacrylamide-functionalized gelatin hydrogel, can be used for three-dimensional trophoblast spheroid motility assays. It can resolve quantifiable differences in outgrowth area and viability in the presence of a known invasion promoter and a known invasion inhibitor. ....

United States , University Of Illinois , Brendan Harley , Johna Jansen , Johnp Fisher , Antoniosg Mikos , Heungsoo Shin , Xiumei Wang , Katja Schenke Layland , Tissue Engineering Regenerative Medicine International Society , Tissue Engineering Co , University Of Maryland , Mary Ann Liebert Inc , Hanyang University , Fischell Family Distinguished Professor Department , Louis Calder Professor At Rice University , Radboud University , University Of Illinois At Urbana Champaign , Tsinghua University , Eberhard Karls University , Tissue Engineering , Tissue Engineering Co Editor In Chief John , Fischell Family Distinguished Professor , Department Chair , Engineering Complex Tissues , Co Editors In Chief Antonios ,