Credit: Richard Hooley/UCR
Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they ve been extremely difficult to detect until now.
Using what they describe as a chemical nose, UC Riverside chemists are able to smell when bits of DNA are folded in unusual ways. Their work designing and demonstrating this system has been published in the journal
Nature Chemistry. If a DNA sequence is folded, it could prevent the transcription of a gene linked to that particular piece of DNA, said study author and UCR chemistry professor Wenwan Zhong. In other words, this could have a positive effect by silencing a gene with the potential to cause cancer or promote tumors.
Unique system detects small changes in DNA structures
Small changes in the structure of DNA have been implicated in breast cancer and other diseases, but they ve been extremely difficult to detect until now.
Using what they describe as a chemical nose, UC Riverside chemists are able to smell when bits of DNA are folded in unusual ways. Their work designing and demonstrating this system has been published in the journal
Nature Chemistry.
If a DNA sequence is folded, it could prevent the transcription of a gene linked to that particular piece of DNA. In other words, this could have a positive effect by silencing a gene with the potential to cause cancer or promote tumors.
We have the opportunity for more targeted contact tracing, Hyde Park Superintendent Aviva Kafka said at a school board meeting Thursday. A few weeks ago, the consensus was we should continue with the approach we ve been using, since our approach was so successful . over the past few weeks we are hearing from folks they are rethinking that.
She said the plan, approved by the Dutchess County Department of Behavioral and Community Health and to be implemented after spring break, calls for quarantining students only when one of them comes within a six-foot radius of an individual who tested positive, rather than everyone in a given room or building.
Toggle open close 14 May 31, 1984 THE ROOTS OF THE PHILIPPINES ECONOMIC TROUBLES, INTRODUCTION Economic and political indicators, like appearances, are often deceiving. In mid-1983, the Republic of the Philippines appeared to be on the road to eccnomic recovery and political stability. After more than two years of deep depression, export prices had rebounded upward, industrial production had increased., inflation had fallen from double digits to 7 percent, and govern- ment spending had been slashed 30 percent below the 1982 level. The political situation, which in the past always affected economic growth, also appeared stable. Martial law had been lifted in January 1981, presidential and barangay (city ward and rural village leaders) elections were held in April 1981 and June 1982 respectively, and the political opposition was in disarray. From all appearances, popular support for the government ran high, and the position of President Ferdinand E. Marcos was secure.
Richard Hooley spoke to us this lunchtime about exemption clauses.
Interpretation
He began by quoting from Andrew Burrows’ A Restatement of the English Law of Contract (which has recently been updated) and its excellent summary of contractual interpretation. Paraphrased it says:
Ask what the clause, “viewed in the light of the whole contract, would mean to a reasonable person having all the relevant background knowledge reasonably available to the parties at the time the contract was made”.
When doing this consider the (a) natural meaning of the words used (b) the overall purpose of the clause and the contract (c) the facts and circumstances known by the parties and (d) commercial common sense.