Novel organoid models illuminate path to cervical cancers
How do tumors develop in the cervix? Many new details are now known about this question. This is also thanks to Dr. Cindrilla Chumduri from the Biocentre at the University of Würzburg.
Organoids are increasingly being used in biomedical research. These are organ-like structures created in the laboratory that are only a few millimeters in size. Organoids can be used to study life processes and the effect of drugs. Because they closely resemble real organs, they offer several advantages over other cell cultures.
Now there are also organoid models developed for the cervix. This part of the female body is particularly at risk to develop cancers. By creating novel organoid models, a group led by Cindrilla Chumduri (Würzburg), Rajendra Kumar Gurumurthy (Berlin) and Thomas F. Meyer (Kiel) have established a unique approach to studying the biology of the cervix and identify key turning points in cancer development.