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Colitis Risk Lowered in Mice by Replacing Missing Gut Microbes in Early Development June 9, 2021 Ulcerative colitis (UC) is an inflammatory disease that affects the colon and rectum. It is believed that genetic factors, host immune system disorders, intestinal microbiota dysbiosis, and environmental factors contribute to the pathogenesis of UC. Previous studies have linked missing microbes to ulcerative colitis. These microbes make metabolites that help keep the gut healthy. Now a new study by researchers at the University of Chicago (UChicago) demonstrates that restoring a single microbial species, Bacteroides sp. CL1-UC (Bc), to the gut microbiome at a key developmental timepoint can prevent antibiotic-induced colitis in a mouse model of the condition.

Martin boyerEugene changJun miyoshiUniversity of chicago uchicagoKyorin university school of medicineKyorin university schoolமார்டின் பையன்யூஜின் சாங்பல்கலைக்கழகம் ஆஃப் சிகாகோ உசிக்கோ