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Researchers devise more efficient, enduring CAR gene therapy to combat HIV

Researchers devise more efficient, enduring CAR gene therapy to combat HIV
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Mayra carrilloIrvin chenHeather martinValerie rezekOtto yangJeromea zackPhilip hamidAnjie zhenScott kitchenமெய்ரா கரில்லோஇவிந் சென்ஹீத்தர் மார்டின்ஒட்தோ யாங்பிலிப் ஹமிட்ஸ்காட் சமையலறை

Researchers devise more efficient, enduring CAR gene therapy to combat HIV

UCLA RESEARCH BRIEF National Institute of Allergy and Infectious Diseases (NIAID) The improved therapy engineers the body’s immune response against HIV rather than waiting for the virus or parts of the virus to induce a response. (Image: A T cell infected with HIV.) Enrique Rivero | FINDINGS A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule. This new approach to CAR T gene therapy a type of immunotherapy that involves genetically engineering the body’s own blood-forming stem cells to create HIV-fighting T cells has the potential to not only destroy HIV-infected cells but to create “memory cells” that could provide lifelong protection from infection with the virus that causes AIDS.

United statesMayra carrilloIrvin chenHeather martinValerie rezekOtto yangJeromea zackPhilip hamidAnjie zhenCalifornia institute for regenerative medicineNational institutes of healthScott kitchenNational institutesCalifornia instituteRegenerative medicineLongitudinal investment

Vigil held for Springdale woman who was killed in Pennsylvania

Chyna Carrillo would have turned 25 Wednesday, so her family held a vigil to honor her memory.

United statesChynaa carrilloMayra carrilloSpringdale womanஒன்றுபட்டது மாநிலங்களில்மெய்ரா கரில்லோஸ்பிரிங்டேல் பெண்

The recent deaths of trans people of color in Western Pennsylvania signal an alarming trend of violence

CP Photo: Kaycee Orwig Trans YOUniting held a candlelight vigil on Sun., Feb. 28 outside the City County Building to honor four lives that were lost in the past two weeks. Four trans people of color have died in Western Pennsylvania in February, three of whom were killed within one week. Chyna Carrillo was killed in Lawrence County, an hour north of Pittsburgh, on Feb. 18, and siblings Jasmine Cannady and Jeffrey “JJ” Bright were killed in Ambridge, just 30 minutes from the city, on Feb. 22. Audura Belle also died earlier this month due to lack of health care, according to statements from her friends and family.

United statesLawrence countyBeaver countyTori cooperMarya carrilloMayra carrilloKaycee orwigDonald trumpJasmine cannadyChyna carrilloAudura belleYouniting dena stanelyJuan carter hernandezTransgender justice initiativeNational centerNational institutes of health

A Pennsylvanian woman becomes the seventh trans death this year

Chyna Carrillo’s murder has marked the seventh trans death in the US this year. Carrillo, who also went by Chyna Cardenas, was brutally killed on the morning of February 18, 2021. Police were called to Carrillo’s house at 11AM after Juan Carter Hernandez was seen beating her with a “blunt object” in broad daylight, according to LGBTQ+ Nation. Hernandez is suspected to have been a previously convicted criminal. A man with the same name was seemed guilty for murdered his wife in 2013 and an ex-girlfriend, Kandace Hernandez, in July 2011. Once officers arrived, they ordered Hernandez to stop his attack. After failing to comply with police directions, the perpetrator was fatally shot at the scene.

United statesMayra carrilloKandace hernandezChyna cardenasJuan carter hernandezChyna carrilloNew wilmingtonCommunity engagementTransgender justice initiative tori cooperஒன்றுபட்டது மாநிலங்களில்மெய்ரா கரில்லோகந்தசெ ஹெர்னாண்டஸ்சய்னா கார்டெனாக்கள்ஜுவான் கார்ட்டர் ஹெர்னாண்டஸ்சய்னா கரில்லோபுதியது வில்மிங்டன்