Among the most promising therapeutic options for individuals with coronavirus disease 2019 (COVID-19) are monoclonal antibodies (mAbs). In this study, Jones et al . identified, characterized, and tested one such mAb, LY-CoV555, in vitro and in vivo. They found that LY-CoV555 bound to the severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2) spike protein and prevented its interaction with angiotensin-converting enzyme 2. Prophylactic treatment with LY-CoV555 protected the upper and lower respiratory tracts of nonhuman primates from becoming infected with SARS-CoV-2. Together, these data support the clinical use of LY-CoV555 for treating patients with COVID-19.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies are a key class of therapeutics that may bridge widespread vaccination campaigns and offer a treatment solution in populations less res
Apr 23 2021 Read 8 Times
Author: Thermo Fisher Scientific on behalf of Thermo Fisher Scientific (UK) Ltd
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-OES instruments have evolved rapidly in recent years. This evolution has been driven by the need for performing the measurements faster and improving the robustness of the technique.
Measurement stability in complex and challenging matrices is important alongside instrument uptime and a reduction in user maintenance. The Thermo Scientific™ iCAP™ PRO Series ICP-OES incorporates a vertical torch design, providing not only the smallest footprint ICP-OES on the market but also delivering unchallenged robustness.
A vertical torch orientation for a radial-only instrument is the industry standard; however, for a dual view instrument there are two major challenges that need to be addressed to ensure robustness. The first of these challenges is the deposition of sample matrix on the plasma interface, and the second is corrosion of the i