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( A) Distribution of observed first-positive viral loads for 25,381 subjects according to clinical status (6110 PAMS, 9519 Hospitalised, 9752 Other) and age group. ( B) Age-viral load association with observed viral loads and confidence intervals as circles (with size indicating subject count) with vertical lines, and model-predicted viral loads and credible intervals as a black roughly-horizontal line with grey shading. ( C) Overlapping age histograms according to subject clinical status. Because inclusion in the study required a positive RT-PCR test result, and testing is in many cases symptom-dependent, the study may have a proportion of PAMS cases that differs from the proportion in the general population.

Eteläuomen läiHong kongUnited kingdomLeonie meinersManuel holtgreweStephen kisslerOliver stolpeUdo gierathsDieter beuleGerman federal ministry of educationInstitute of virologyEuropean commissionBerlin institute of healthResearch clinicBerlin institute of virologyInstitute of virology at charit