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IMAGE: Confocal micrographs of mouse small intestine with the Red2Onco technology. With Red2Onco, the oncogenic mutant clones (Red clones), and normal or wild-type clones (Yellow or Cyan clones) can be labeled. view more
Credit: ©Yum/IMBA
Studies on cancer are limited by the threshold at which cellular transformations become clinically detectable. However, the very initial phase on the way to malignancy is histologically invisible, as the process originates from one single cell. In this early phase, a so-called seeding cell acquires an initial pro-cancerous mutation, also known as the first oncogenic hit , while being completely surrounded by normal tissue. To overcome the detection barrier, a team of researchers around IMBA group leader Bon-Kyoung Koo and University of Cambridge group leader Professor Benjamin D. Simons developed a laboratory system to dissect the pre-cancerous steps that remained under the radar up until present.
Момент творения: в лаборатории вырастили сердце человеческого эмбриона — видео
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Требуем немедленно покинуть территорию Армении, в противном случае вопрос будет решен, в том числе, путем применения силы – Минобороны РА
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NEWSru com :: Григорий Юдин: Европа не может существовать с выколотой Беларусью по центру
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Credit: Peter Duchek
Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal
Nature Communications and could be adapted to many more pathogens.
The COVID-19 pandemic has lasted more than a year and continues to impact our lives tremendously. Although some countries have launched speedy vaccination campaigns, many still await large-scale immunization schemes and effective antiviral therapies - before that happens, the world urgently needs to regain a semblance of normalcy.
One way to bring us closer to that point is massive parallel testing. Molecular tests that detect the presence of SARS-CoV-2 have become the best way to isolate positive cases and contain the spread of the virus. Several methods have come forward, some that detect viral proteins from nasopharyngeal swabs (such as antigen tests), and some that detect the presence of v