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Researchers Develop a Biosensor for Measuring Extracellular Hydrogen Peroxide Concentrations
Several processes in the human body are regulated by biochemical reactions involving hydrogen peroxide (H
2O
2). Although it can act as a secondary messenger , relaying or amplifying certain signals between cells, H
2O
2 is generally toxic because of its oxidant character.
The latter means that it converts (oxidizes) biochemical molecules like proteins and DNA. The oxidizing property of H
2O
2 is of potential therapeutic relevance for cancer, though: deliberately causing tumor cells to increase their H
2O
In light of this, but also for monitoring pathologies associated with H
2O
Leonardo-puppulinNano-life-science-instituteKanazawa-universityநானோ-வாழ்க்கை-அறிவியல்-நிறுவனம்கனசாவா-பல்கலைக்கழகம்New biosensor measures extracellular hydrogen peroxide levels with nanometer-resolution
Several processes in the human body are regulated by biochemical reactions involving hydrogen peroxide (H
2O
2).
2O
2 is generally toxic because of its oxidant character. The latter means that it converts (oxidizes) biochemical molecules like proteins and DNA.
The oxidizing property of H
2O
2 is of potential therapeutic relevance for cancer, though: deliberately causing tumor cells to increase their H
2O
2 concentration would be a way to destroy them. In light of this, but also for monitoring pathologies associated with H
2O
2 overproduction, it is crucial to have a means to reliably quantify hydrogen peroxide concentrations in the extracellular environment.
Leonardo-puppulinEmily-hendersonNano-life-science-instituteKanazawa-universityBiosensorHydrogen-peroxideCancerCellCompoundConjugationDnaFrequency