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Todos Medical Ltd hires CRO Innvocept Global Solutions to manage two Tollovir coronavirus trials in India

Todos Medical Ltd hires CRO Innvocept Global Solutions to manage two Tollovir coronavirus trials in India
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La empresa Todos Medical de Tel Aviv inicia un ensayo de un inhibidor de proteasa para tratar Covid-19

La empresa Todos Medical de Tel Aviv inicia un ensayo de un inhibidor de proteasa para tratar Covid-19
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Todos Medical Launches Phase 2 Clinical Trial of Its Antiviral 3CL Protease Inhibitor NLC-V-01 (Tollovir) in Hospitalized COVID-19 Patients

Todos Medical Launches Phase 2 Clinical Trial of Its Antiviral 3CL Protease Inhibitor NLC-V-01 (Tollovir) in Hospitalized COVID-19 Patients
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Todos Medical starts trial of protease inhibitor to treat Covid-19

Todos Medical starts trial of protease inhibitor to treat Covid-19 20 Apr 2021 (Last Updated April 20th, 2021 10:48) Todos Medical has started a Phase II clinical trial to evaluate the safety and efficacy of its antiviral NLC-V-01 (Tollovir), a potent 3CL protease inhibitor to treat hospitalised Covid-19 patients. Share Article Todos Medical has started a Phase II clinical trial to evaluate the safety and efficacy of its antiviral NLC-V-01 (Tollovir), a potent 3CL protease inhibitor to treat hospitalised Covid-19 patients. The 77-patient, randomised, double blind, placebo-controlled trial is being conducted at Shaare Zedek Medical Center in Jerusalem, Israel. Todos Medical is developing the therapeutic agent Tollovir through a joint venture with NLC Pharma.

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Todos Medical Ltd initiates Phase 2 clinical trial in Israel of Tollovir for the treatment of hospitalized coronavirus patients

In addition, the secondary endpoints of the trial being examined are: Rate of change of measured parameters Rate of change in vital signs (blood pressure, heart rate, respiratory rate, saturation, and body temperature) Time from the 1st day of receiving NLC-V treatment to negative RT-PCR test result COVID-19 related deaths Incidence and duration of time on supplemental oxygen “I am glad that my pioneering academic work over the last 30 years on 3CL mechanisms has made such a significant impact, and that it is finally being recognized by leading pharmaceutical companies as a key target in the war against COVID-19 that could yield an easy to administer oral antiviral therapeutic capable of stopping SARS-CoV-2 replication, independent of different mutations that are emerging at the site of spike protein,” said Dr Dorit Arad, co-founder and chief scientific officer of NLC Pharma in a statement.

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