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IMAGE: Schematic of bubble membrane showing the influence of membrane stiffener and membrane softener in the phospholipid packing.
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Credit: Amin Jafari Sojahrood and Al C. de Leon
If you were given ultrasound in a word association game, sound wave might easily come to mind. But in recent years, a new term has surfaced: bubbles. Those ephemeral, globular shapes are proving useful in improving medical imaging, disease detection and targeted drug delivery. There s just one glitch: bubbles fizzle out soon after injection into the bloodstream.
Now, after 10 years work, a multidisciplinary research team has built a better bubble. Their new formulations have resulted in nanoscale bubbles with customizable outer shells so small and durable that they can travel to and penetrate some of the most inaccessible areas in the human body. ....

Amin Jafari Sojahrood , Michael Kolios , Agataa Exner , Department Of Radiology , National Institutes Of Health , Case Western Reserve University Coulter Translational Partnership , Department Of Physics At Ryerson University , Case Western Reserve University School Of Medicine , National Institute Of Biomedical Imaging , Institute For Biomedical Engineering , Health Affairs , Office Of The , Case Western Reserve University School , Ryerson University , Biomedical Engineering , Precisely Controllable Acoustic Response , Shell Stabilized Nanobubbles , Shrinking Down , Biomedical Imaging , National Institutes , Assistant Secretary , Prostate Cancer , Chemistry Physics Materials Sciences , Biomechanics Biophysics , Medicine Health , Researchers Scientists Awards ,