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Experimental drug shows potential against Alzheimer s disease

Credit: Albert Einstein College of Medicine April 22, 2021 (BRONX, NY) Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer s disease in mice. The drug works by reinvigorating a cellular cleaning mechanism that gets rid of unwanted proteins by digesting and recycling them. The study was published online today in the journal Cell. Discoveries in mice don t always translate to humans, especially in Alzheimer s disease, said co-study leader Ana Maria Cuervo, M.D., Ph.D., the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases, professor of developmental and molecular biology, and co-director of the Institute for Aging Research at Einstein. But we were encouraged to find in our study that the drop-off in cellular cleaning that contributes to Alzheimer s in mice also occurs in people with the disease, suggesting that our drug may also work in humans. In the 1990s, Dr. Cuervo discovered

Mark Winkler & David Benoit: Old Friends CD 2021

Release Dates for Broadway CDs, Streaming, Cast Albums, Solo Releases, iTunes & More Mark Winkler & David Benoit: Old Friends 2021 Collection of some of the duo s favorites songs by some of their favorite composers, as well as three original tunes. I ve Got Just About Everything, Sweet Kentucky Ham, Better Than Anything, The Shadow of Your Smile, Two for the Road, Old Friends / Bookends, When This Love Affair Is Over, I Think It s Going to Rain Today, In a Quiet Place (Kei s Song), I Wish I d Met You, Dragonfly, Thirty Years, Some Other Time. The Story Pirates will release their fourth full-length album, The Strawberry Band, on April 9th, and DJ Squirm-a-Lot is throwing a huge party on Zoom the night before, which is Thursday, April 8th at 7 pm EST, 6 pm CST, 4 pm PST.

Mel Brooks Young Frankenstein OLC CD 2021

Release Dates for Broadway CDs, Streaming, Cast Albums, Solo Releases, iTunes & More Mel Brooks Young Frankenstein OLC 2021 Live recording made over several performances in the West End at the Garrick Theatre. Score by Mel Brooks ( Puttin on the Ritz by Irving Berlin). Cast includes Ross Noble, Lesley Joseph, Dianne Pilkington, Patrick Clancy. Overture, The Brain, Please Don t Touch Me, Together Again, Roll in the Hay, He Vas My Boyfriend, It Could Work, Hang Him Till He s Dead, The Experiment, He Vas My Boyfriend Reprise, Welcome to Transylvania, Transylvania Mania, He s Loose, Listen to Your Heart, Surprise, Someone, Puttin on the Ritz, Deep Love, Hang the Doctor, Deep Love Reprise and Finale, Finale - Together Again, The Bows, Exit Music. Mastered by Andy Water at Abbey Road Studios. Produced and mixed By Paul Gatehouse. Executive Produced By Mel Brooks and Kevin Salter. P

Neuroscientist David Sulzer To Release Debut Book MUSIC, MATH, AND MIND: THE PHYSICS AND NEUROSCIENCE OF MUSIC

David Sulzer s debut book, Music, Math, and Mind, offers a lively exploration of the mathematics, physics, and neuroscience that underlie music in a way that readers without scientific background can follow. Dr. Sulzer, also known in the musical world as Dave Soldier, explains why the perception of music encompasses the physics of sound, the functions of the ear and deep-brain auditory pathways, and the physiology of emotion. He delves into topics such as the math by which musical scales, rhythms, tuning, and harmonies are derived, from the days of Pythagoras to technological manipulation of sound waves. Sulzer makes accessible a vast range of material-styles from around the world to canonical composers to hip-hop, the history of experimental music, and animal music by songbirds, cetaceans, bats, and insects.

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