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Self-Assembling Nanomaterial can Reduce Damage Due to Inflammatory Diseases Written by AZoNanoApr 15 2021 A new self-assembling nanomaterial designed by biomedical engineers from Duke University stimulates major cells in the immune system that can help reduce damage caused by inflammatory disorders. The graphic shows the peptide nanofiber bearing complement protein C3dg (blue) and key components of the TNF protein, which include B-cell epitopes (green) and T-cell epitopes (purple). Image Credit: Chelsea Fries. In psoriasis mouse models, the nanofiber-based medication has been demonstrated to reduce the damaging inflammation as successfully as a gold-standard treatment. The overproduction of signaling proteins, known as cytokines, is one of the hallmarks of inflammatory disorders, such as psoriasis, Crohn’s disease and rheumatoid arthritis. These signaling proteins are known to cause inflammation.

North carolinaUnited statesDuke universityJoel collierKelly hainlineCarolina biotechnology centerNational institutes of healthResearch fellowship programImage creditBiomedical engineeringNational academyGraduate studentNational institutesNorth carolina biotechnology centerவடக்கு கரோலினாஒன்றுபட்டது மாநிலங்களில்