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Kojin Therapeutics Debuts to Solve Difficult Diseases Through Cell Behavior

Published: Jun 09, 2021 By Mark Terry Kojin Therapeutics launched with a $60 million Series A to initially focus on oncology and cell state biology. The round was led by Polaris Partners, Newpath Partners, and Cathay Health, affiliated to Cathay Capital. Participants included Leaps by Bayer, AbbVie, Eventide Asset Management, Alexandria, the Dana-Farber Cancer Institute’s Binney Street Capital, and several family offices. The approach came out of the laboratoryof Stuart Schreiber, Harvard University professor and co-founder of the Broad Institute. Co-founders of Kojin include Benjamin Cravatt, Stephanie Dougan and Vasanthi Viswanathan. The company’s technology is ferroptosis-based drug discovery, which is to say, iron-dependent cell death. Kojin says that difficult-to-treat diseases, which includes drug-resistant cancers, involve diseased cells that are sensitive to ferroptosis.

United statesAl iskandariyahHarvard universityDana farber cancer instituteJurgen eckhardtAmir nashatBenjamin cravattStephanie douganJoel barrishSteve davidsenNagesh mahanthappaSusan langerVasanthi viswanathanNortonb gilulaStuart schreiberKay ahn

Jumping genes can prevent blood cancers: Study

Jumping genes can prevent blood cancers: Study By IANS | 4 Views Gallbladder, biliary tract cancer cases up 76% in 3 decades. Image Source: IANS News New York, April 9 : US scientists have found that transposons, also known as jumping genes, can protect against certain blood cancers and help develop new therapeutic targets. Transposons are DNA sequences that can move, or jump, from one location in the genome to another when activated. These jumping genes are a source of genetic mutations responsible for a number of human diseases. The findings, published in the journal Nature Genetics, can help predict how patients will respond to cancer therapies and find new therapeutic targets for acute myeloid leukemia (AML) the deadliest type of blood cancer in adults and children.

New yorkUnited statesJian xuChildren medical center research instituteUniversity of texas southwesternNature geneticsMedical center research instituteTexas southwesternAssociate professorபுதியது யார்க்ஒன்றுபட்டது மாநிலங்களில்ஜியான் ஐயூகுழந்தைகள் மருத்துவ மையம் ஆராய்ச்சி நிறுவனம்பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் தென்மேற்குஇயற்கை ஜெநெடிக்ஸ்மருத்துவ மையம் ஆராய்ச்சி நிறுவனம்

Jumping genes can prevent blood cancers: Study - INDIA New England News

Jumping genes can prevent blood cancers: Study - INDIA New England News
indianewengland.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from indianewengland.com Daily Mail and Mail on Sunday newspapers.

New yorkUnited statesJian xuChildren medical center research instituteUniversity of texas southwesternNature geneticsMedical center research instituteTexas southwesternAssociate professorபுதியது யார்க்ஒன்றுபட்டது மாநிலங்களில்ஜியான் ஐயூகுழந்தைகள் மருத்துவ மையம் ஆராய்ச்சி நிறுவனம்பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் தென்மேற்குஇயற்கை ஜெநெடிக்ஸ்மருத்துவ மையம் ஆராய்ச்சி நிறுவனம்

Transposons can protect against certain blood cancers

Transposons can protect against certain blood cancers
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

Jian xuEmily hendersonChildren medical center research instituteMedical center research instituteNature geneticsStudy senior authorAssociate professorMedical center researchஜியான் ஐயூஎமிலி ஹென்டர்சன்குழந்தைகள் மருத்துவ மையம் ஆராய்ச்சி நிறுவனம்மருத்துவ மையம் ஆராய்ச்சி நிறுவனம்இயற்கை ஜெநெடிக்ஸ்படிப்பு மூத்தவர் நூலாசிரியர்இணை ப்ரொஃபெஸர்மருத்துவ மையம் ஆராய்ச்சி

Scientists discover jumping genes that can protect against blood cancers

E-Mail IMAGE: Zhimin Gu, Ph.D., postdoctoral fellow, Children s Medical Center Research Institute at UT Southwestern (CRI), and Jian Xu Ph.D., associate professor, CRI view more Credit: UT Southwestern Medical Center DALLAS - April 8, 2021 - New research has uncovered a surprising role for so-called jumping genes that are a source of genetic mutations responsible for a number of human diseases. In the new study from Children s Medical Center Research Institute at UT Southwestern (CRI), scientists made the unexpected discovery that these DNA sequences, also known as transposons, can protect against certain blood cancers. These findings, published in Nature Genetics, led scientists to identify a new biomarker that could help predict how patients will respond to cancer therapies and find new therapeutic targets for acute myeloid leukemia (AML), the deadliest type of blood cancer in adults and children.

United statesYuxuan liuAlec zhangJian xuJohn abramsZhimin guScholar in cancer researchNational institutes of healthChildren medical center dallasLeukemia texas foundationAmerican society of hematology scholarWelch foundationChildren medical center research instituteUt southwestern medical centerChildren medical center foundationLeukemia lymphoma society scholar