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Deion Sanders Opens Up About Dealing with Depression, Suicidal Thoughts

COVID-19-Associated Seizures May be Common, Linked to Higher Risk of Death

Study examines the prevalence and risk factors for non-convulsive seizures among patients hospitalized with COVID-19 Boston – COVID-19 can have damaging effects on organs throughout the body, including the brain. A new study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) and Massachusetts General Hospital (MGH) demonstrated that some patients hospitalized with COVID-19 experience non-convulsive seizures, which may put them at higher risk of dying. The findings are published in the Annals of Neurology. “We found that seizures can happen in patients with severe COVID-19 infections, even those without any prior neurologic history, and that they are associated with worse outcomes,” says co-author Mouhsin Shafi, MD, PhD, an investigator in the Department of Neurology at BIDMC, Medical Director of the BIDMC electroencephalogram

Nanoparticle drug-delivery system developed to treat brain disorders

 E-Mail Use of the delivery system in mouse models results in unprecedented siRNA penetration across the intact blood brain barrier Technology could offer potential for a variety of human neurological disorders In the past few decades, researchers have identified biological pathways leading to neurodegenerative diseases and developed promising molecular agents to target them. However, the translation of these findings into clinically approved treatments has progressed at a much slower rate, in part because of the challenges scientists face in delivering therapeutics across the blood-brain barrier (BBB) and into the brain. To facilitate successful delivery of therapeutic agents to the brain, a team of bioengineers, physicians, and collaborators at Brigham and Women s Hospital and Boston Children s Hospital created a nanoparticle platform, which can facilitate therapeutically effective delivery of encapsulated agents in mice with a physically breached or intact BBB. In a mouse mod

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