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BOSTON, Jan. 8, 2021 /PRNewswire/ Emulate, Inc., a leading provider of advanced in vitro models, today announced an application roadmap for their market leading organ-on-a-chip technology that expands beyond small molecule applications and addresses the growing focus on targeted and advanced biologics within drug development. These new human organ models enable the technology to be used within stages of the drug discovery and development process that are iterative, including, target identification and validation, mechanistic studies, drug delivery and biomarker identification.
Today, biologic drugs comprise 40 percent of the drug development pipeline, a percentage that is expected to continue to grow in the coming years. Biologics are highly specific and tailored to human pathways and targets, often involving complex engagement of immune cells. Current
Published: Dec 21, 2020
BOSTON, Dec. 21, 2020 /PRNewswire/ Emulate, Inc., a leading provider of advanced
in vitro models, today unveiled the Emulate Brain-Chip, which is designed for neuroscience researchers investigating neuroinflammatory disease and for drug developers seeking to improve drug discovery for neurodegenerative diseases such as Alzheimer s and Parkinson s. The comprehensive model incorporates cells from the human brain, including the blood-brain barrier, in a dynamic microenvironment which enables cell-cell interaction.
Emulate Organ-Chips, including the Brain-Chip, are designed to enable researchers to investigate the safety and efficacy of therapeutic treatments in development, in order to reduce the high drug development failure rates that result from a poor understanding of drug mechanism of action, toxicity, pharmacokinetic profile, or overall applicability and translation of animal and