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An Essential Balancing Act: Neurons Adapt to Stay Steady


Weizmann Institute of Science
Our brain has On and Off switches for all its activities, and maintaining a balance between the two is crucial for our health and well-being. For instance: Epileptic seizures occur when the On signals run amok in the cortex, while people with Parkinson’s disease have difficulty using their muscles because of an excess of Off signals in the brain’s motor regions. In memory circuits, an overzealous On can force irrelevant memories upon us, as in posttraumatic stress disorder, whereas an overly active Off can prevent us from remembering anything at all.
In a new study reported in the Proceedings of the National Academy of Sciences (PNAS), researchers at the Weizmann Institute of Science, in collaboration with scientists from the University of Tübingen, have revealed how the brain keeps the On-Off balance steady. They discovered that this balance is programmed into the basic mechanisms through which individual neurons connect with one another ....

Eyal Weinreb , Elisha Moses , Nirit Sukenik , Menahem Segal , Oleg Vinogradov , Anna Levina , Weizmann Physics Of Complex Systems Department , Proceedings Of The National Academy Sciences , Weizmann Institute Of Science , Weizmann Neurobiology Department , National Academy , Weizmann Institute , Complex Systems Department , Neurobiology Department , Post Traumatic Stress Disorder , எலிஷா மோஸஸ் , அண்ணா லெவினா , வெய்ஸ்மேன் நிறுவனம் ஆஃப் அறிவியல் , வெய்ஸ்மேன் நரம்பியல் துறை , தேசிய கலைக்கழகம் , வெய்ஸ்மேன் நிறுவனம் , சிக்கலான அமைப்புகள் துறை , நரம்பியல் துறை , போஸ்ட் அதிர்ச்சிகரமான மன அழுத்தம் கோளாறு , கொட்டைவடி நீர் , மன அழுத்தம் ,