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14 have been identified to promote cervical cancer progression, suggesting the important role of circRNAs in cervical cancer tumorigenesis. As for circ 0003221 (also known as circPTK2, chr8:141856358–141900868), it has been demonstrated to be overexpressed in cervical cancer cells.
15 Nevertheless, the role of circ 0003221 in cervical cancer remains largely unclear.
Large evidence has shown that circRNAs can serve as competing endogenous RNAs (ceRNAs), also known as microRNA (miRNA) sponges, via competitively binding to miRNA response elements, thereby regulating the expression of downstream target genes.
16,17 Based on this regulation, circRNAs can function as miRNA sponges to regulate the expression of target genes, forming a regulatory circRNA-miRNA-mRNA network. MiR-758 has been identified to serve as a tumor-suppressing miRNA in cervical cancer.
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Social media posts claim a Canadian lawyer won a case against âforced immunizationâ and the result now has the force of federal law. This is false; vaccination is not mandatory at the federal level in Canada, provinces that require proof of immunization for school attendance allow exemptions, and two vaccine-related cases in which the attorney is involved remain unresolved.
âRocco Galati won the cause against forced immunization in Canada. It is now a federal law,â claims an April 7, 2021 Instagram post.
Screenshot of an Instagram post taken on April 13, 2021
The post appears to be a screenshot of an automatically translated French tweet. The claim was also shared on Facebook.