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Study offers genetic insights into the underlying biology of reproductive aging The age at which women go through menopause is critical for fertility and impacts healthy aging in women, but reproductive aging has been difficult for scientists to study and insights into the underlying biology are limited. Now, scientists have identified nearly 300 gene variations that influence reproductive lifespan in women. Additionally, in mice, they have successfully manipulated several key genes associated with these variants to extend their reproductive lifespan. Their findings, published today in Nature, substantially increase our knowledge of the reproductive aging process, as well as providing ways to improve the prediction of

United kingdomComunidad autonoma de catalunaIgnasi roigJohn perryKatherine ruthKeva hoffmannEmily hendersonUniversity of cambridgeUniversity of copenhagenInstitute of biotechnologyUniversity of exeterResearch councilProfessor eva hoffmannUniversitat autChromosome stabilityUnited kingdom biobank