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New High-Resolution Imaging Technology Reveals COVID-19 Lung Pathology in Space and Time April 1, 2021 Share Using a new method called ‘high parameter imaging mass cytometry’ scientists visualize detailed cellular landscapes of the lung in infectious lung diseases at never-before-seen, single-cell resolution. With this new technique, investigators at Weill Cornell Medicine and New York-Presbyterian target the expression of 36 proteins, to probe into the cellular composition and spatial architecture of human acute lung injury including lung tissue infected by SARS-CoV-2, the coronavirus that causes COVID-19. Nature. The findings provide new insights into the causes of damage in these infectious lung diseases and a detailed resource for future investigations.

New yorkUnited statesAlain borczukOlivier elementoRobert schwartzIsrael englander institute for precision medicineDivision of gastroenterologyPresbyterian weill cornell medical centerWeill cornell medicineNew york presbyterianIsrael englander instituteWeill cornell medical centerComputational biomedicineWorldquant initiativeQuantitative predictionMedical college