3 IMvigor 210
First-line maintenance treatment: JAVELIN Bladder 100
5
Given the above success of immunotherapy in bladder cancer, there is great interest in the possibility of moving immunotherapy into the neoadjuvant disease space. Currently, there are many ongoing clinical trials for neoadjuvant immunotherapy:
6
7 and ABACUS
8 phase II trials. PURE-01 enrolled 143 patients that were treated with 3 cycles of pembrolizumab, resulting in a pT0 rate of 37%. ABACUS enrolled 95 patients that were treated with two cycles of atezolizumab, resulting in a pT0 rate of 31%. Three clinical trials have assessed the utility of immunotherapy combination therapy, including the NABUCCO (ipilimumab + nivolumab x 3), DUTRENEO (durvalumab + tremelimumab x 3), and durvalumab + tremelimumab x 2 (NCT02812420). As follows is a summary of these trials:
Trodelvy More than Doubled Overall Survival as Second-Line Treatment in New ASCENT Subgroup Analysis – Gilead Sciences, Inc. today announced new data from the Phase 3 ASCENT study evaluating Trodelvy ® in relapsed or refractory metastatic triple-negative breast cancer . In this subgroup analysis of brain metastases-negative patients who received only one line of prior systemic therapy in the metastatic setting in .
Number of Domiciliary Care Centres increased, more first-line treatment centres planned. Additional beds also on anvil
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District Collector Navjot Khosa assessing the arrangements for counting of votes at Mar Ivanios College at Vidya Nagar in Nalanchira on Friday | Vincent Pulickal By Express News Service
THIRUVANANTHAPURAM: In the wake of increasing number of Covid-19 patients in Thiruvananthapuram, the district administration is enhancing infrastructure to facilitate better treatment. District collector Navjot Khosa has said there is no shortage of oxygen and all measures have been put in place to aggressively combat Covid-19.
The district has 37 Domiciliary Care Centres (DCCs), 17 Covid First-Line Treatment Centres (CFLTCs) and 16 Covid Second Line Treatment Centres. The number of DCCs has also been increased in view of the increasing number of patients.