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Aggressive brain tumor mapped in genetic, molecular detail


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IMAGE: Pictured are MRI scans of eight patients with glioblastoma, an aggressive brain tumor. A new study led by Washington University School of Medicine in St. Louis has mapped out detailed.
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Credit: ALBERT H. KIM
Glioblastoma is among the most aggressive and devastating of cancers. While rare compared with other cancers, it s the most common type of brain cancer. Even with intensive therapy, relatively few patients survive longer than two years after diagnosis, and fewer than 10% of patients survive beyond five years. Despite extensive studies focused on genomic features of glioblastoma, relatively little progress has been made in improving treatment for patients with this deadly disease. ....

Tao Liu , Marinaa Gritsenko , Jennifere Kyle , Alberth Kim , Liang Bo Wang , Henry Rodriguez , Yize Li , Karin Rodland , School Of Medicine , Siteman Cancer Center At Barnes , National Cancer Institute , National Institutes Of Health , Pacific Northwest National Laboratory , Clinical Proteomic Tumor Analysis Consortium , Washington University School Of Medicine , Environmental Molecular Sciences Laboratory , Division Of Oncology At Washington University , Washington University , Brain Tumor Center At Siteman , Office Of Cancer Clinical Proteomics Research , National Human Genome Research Institute , Case Western Reserve University , Washington University School , National Institutes , Cancer Cell , Proteomic Tumor Analysis Consortium ,