Researchers at the University of Illinois Chicago are a step closer to discovering why it is so difficult for people to withdraw from some antidepressant medications.
Thursday, May 13, 2021
Share On May 6, leaders of the Pennsylvania National Guard awarded Pitt’s Rory Cooper and Garrett Grindle (ENGR ’04, ’07G) the Pennsylvania Veterans Service Award for their work protecting veterans and their caregivers during the pandemic. In April 2020, the University’s Human Engineering Research Laboratories (HERL) pivoted from their usual technology research and development to producing nasal swabs, face shields and other medical supplies to meet demand during the crisis. Their work helped keep VA hospitals open and safe for workers, patients and caregivers. “I am extremely proud of the team at HERL,” Cooper told the VA’s Research Currents publication last spring. “They have risen to the challenge of assisting with VA’s response to COVID-19 and have performed outstandingly. The work of the team at HERL has likely helped slow the spread of the disease and has assisted VA health care providers in saving the lives of vet
When Not What Obese Mice Ate Reduced Breast Cancer Risk
Restricting eating to an eight-hour window, when activity is highest, decreased the risk of development, growth and metastasis of breast cancer in mouse models, report researchers at University of California San Diego School of Medicine, Moores Cancer Center and Veterans Affairs San Diego Healthcare System (VASDSH).
The findings, published in the January 25, 2021 edition of Nature Communications, show that time-restricted feeding a form of intermittent fasting aligned with circadian rhythms improved metabolic health and tumor circadian rhythms in mice with obesity-driven postmenopausal breast cancer.
“Previous research has shown that obesity increases the risk of a variety of cancers by negatively affecting how the body reacts to insulin levels and changing circadian rhythms,” said senior author Nicholas Webster, PhD, professor at UC San Diego School of Medicine and senior research career scientist at VASDSH. “
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A new therapy developed by researchers at Rush University Medical Center is showing success as a way to prevent COVID-19 symptoms in mice.
In a study published in the
Journal of Neuroimmune Pharmacology, mouse models with COVID-19 showed positive results when a small peptide was introduced nasally. The peptide proved effective in reducing fever, protecting the lungs, improving heart function and reversing cytokine storm a condition in which an infection triggers the immune system to flood the bloodstream with inflammatory proteins. The researchers also report success in preventing the disease from progression. This could be a new approach to prevent SARS-CoV-2 infection and protect COVID-19 patients from breathing problems and cardiac issues, said Kalipada Pahan, PhD, the Floyd A. Davis Professor of Neurology at Rush and a Research Career Scientist at the Jesse Brown VA Medical Center. Understanding the mechanism is proving important to developing effective therapi