Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer’s Disease In animal models, the new compound modulated a key enzyme, reducing or eliminating production of problematic protein fragments; human clinical trials needed March 02, 2021 | Scott LaFee
News release
Amyloid plaques are pathological hallmarks of Alzheimer’s disease (AD) clumps of misfolded proteins that accumulate in the brain, disrupting and killing neurons and resulting in the progressive cognitive impairment that is characteristic of the widespread neurological disorder.
In a new study, published March 2, 2021 in the
Journal of Experimental Medicine (JEM), researchers at University of California San Diego School of Medicine, Massachusetts General Hospital and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.
New drug prevents hallmark of Alzheimerâs disease in animals
Written by Timothy Huzar on March 9, 2021 â Fact checked by Hannah Flynn, MS
Alzheimerâs disease affects more than 5 million people in the United States.
There is currently no cure.
A hallmark of Alzheimerâs is the formation of so-called plaques, which affect the functioning of cells in the brain.
In a recent series of studies in animals, scientists have shown that a drug that modulates the behavior of one enzyme reduces the formation of plaques.
Scientists have identified a new drug that is effective at inhibiting the development of plaques, a key sign of Alzheimerâs disease, in the brains of animals.
Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer s Disease scienceblog.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scienceblog.com Daily Mail and Mail on Sunday newspapers.
In a new study, researchers report that they have identified a new drug that could prevent Alzheimer's disease by modulating, rather than inhibiting, a key enzyme involved in the formation of amyloid plaques.
New drug could prevent Alzheimer s by modulating key enzyme involved in amyloid plaque formation news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.