Autism develops differently in girls than boys, new research suggests
Published Tuesday, Apr. 20, 2021, 8:24 pm
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New research has shed light on how autism-spectrum disorder manifests in the brains of girls, prompting the scientists to warn that conclusions drawn from studies conducted primarily in boys should not be assumed to hold true for girls.
The researchers discovered that there is a significant difference in the genes and “genetic burden” that underpin the condition in girls and boys. They also identified specific ways the brains of girls with ASD respond differently to social cues such as facial expressions and gestures than do those of girls without ASD.
Study reveals new clues to sex differences in autism
It is well established that autism occurs much more frequently in boys than in girls, and that girls seem to have a greater resilience to developing the condition. It has been unclear, however, why that is.
In a new Yale-led study, researchers find that autism may develop in different regions of the brain in girls than boys and that girls with autism have a larger number of genetic mutations than boys, suggesting that they require a larger genetic hit to develop the disorder.
The findings appear in the April 16 edition of the journal
Study sheds light on how autism manifests in the brains of girls
New research has shed light on how autism-spectrum disorder (ASD) manifests in the brains of girls, prompting the scientists to warn that conclusions drawn from studies conducted primarily in boys should not be assumed to hold true for girls.
The researchers discovered that there is a significant difference in the genes and genetic burden that underpin the condition in girls and boys. They also identified specific ways the brains of girls with ASD respond differently to social cues such as facial expressions and gestures than do those of girls without ASD.
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IMAGE: A team led by Kevin Pelphrey, PhD, a top autism expert at the University of Virginia School of Medicine, discovered that there is a significant difference in the genes and. view more
Credit: Dan Addison | UVA Communications
New research has shed light on how autism-spectrum disorder (ASD) manifests in the brains of girls, prompting the scientists to warn that conclusions drawn from studies conducted primarily in boys should not be assumed to hold true for girls.
The researchers discovered that there is a significant difference in the genes and genetic burden that underpin the condition in girls and boys. They also identified specific ways the brains of girls with ASD respond differently to social cues such as facial expressions and gestures than do those of girls without ASD.