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Escherichia coli, researchers incorporated several unnatural amino acids into bacterial proteins. STEVE GSCHMEISSNER/Science Source
New approach to rewriting bacteria’s genetic code could lead to novel medicines
Jun. 3, 2021 , 4:10 PM
Virtually all living organisms construct their proteins from combinations of 20 different amino acids. To add new amino acids to the mix, scientists have re-engineered genes and other bits of protein-building machinery, resulting in proteins with unique chemical properties useful in making drugs. But the work is laborious and can typically only add one new amino acid at a time.
Now, researchers have opened the floodgates to doing much more. They report today that a broad rewrite of a bacterium’s genome lets them add numerous novel amino acids to one protein. The work could open new ways to synthesize antibiotics and antitumor drugs.
Scientists created a synthetic genome for a bacterium by stringing together building blocks of DNA and the new genome made the microbe immune to viral infection.
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Details 14 April 2021
Hewlett Packard Enterprise (HPE) and financial compliance solutions provider Tookitaki have announced a collaboration that will utilise AI in the fight against money laundering.
Offering the service to banks and financial institutions across APAC, it combines Tookitaki s AI-powered anti-money laundering solution with HPE GreenLake for Big Data. This combined effort enables clients to create a central big data platform to perform AI analytics and enable AI solutions against money laundering, with the agility, flexibility and scalability of the cloud experience.
UOB is the first financial institution to buy in to the new solution, enhancing its operational abilities to combat money laundering through AI. The bank was also able to customise Tookitaki s AI to meet its specific needs. The bank screens 60,000 account names monthly to determine if they belong to people or entities on global regulatory watch lists, and with the A