All licensed vaccines are extremely effective in preventing severe cases of Covid-19, a disease that has killed around three million people worldwide in the space of one year. However, there are still individuals who are more afraid of the vaccine than of the virus. The focus now is on the Oxford-AstraZeneca and Janssen vaccines, after dozens of those who were vaccinated Ââ about 1 in 100,000 â developed a very rare form of potentially lethal blood clots.
Below is a sample of risk-versus-benefit calculations. While approximate, they are useful for understanding the kind of figures used by drug regulatory agencies. We start by looking at a general scenario of 100,000 adults of all ages over a period of four months with an incidence of Covid-19 that reflects the rates experienced in 2021 in Spain:
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The family of 71-year-old Juan Antonio Manrique had put him âin a bubble.â In the midst of the pandemic, this chronic kidney patient required dialysis three times a week, and was considered high risk from the coronavirus. âHe was very weak,â explains his daughter Encarnación. âWe couldnât even celebrate his 50th wedding anniversary.â Juan Antonio was forced to get in an ambulance every other day to go for his dialysis, which he received alongside other patients. It was a half-hour journey between Roquetas de Mar (AlmerÃa) and the capital of the province, a trip that he also shared with other kidney patients. He ended up catching the virus and died after developing Covid-19, as did the other three patients with whom he traveled in the ambulance. It is not known whether the vehicle was the point of contagion.