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Cellular Messengers of Neural Development Identified

  Summary: Researchers unveil the role of cytonemes, thin cell projections, in neural development. These hair-like structures facilitate direct signal transport across cells, impacting nervous system development. By visualizing cytonemes’ function, the researchers discovered their role in establishing signaling gradients and the transport of critical molecules like sonic hedgehog during mammalian tissue development. Compromised cytoneme […] ....

Stacey Ogden , Emma Selner , Jeffrey Steinberg , Alfonso Lavado , Camenzind Robinson , Yong Dong Wang , Amanda Johnson , Elizabeth Cleverdon , Shondra Pruett Miller , Yan Zhang , Eric Hall , Christina Daly , Alex Carisey , Shariq Ansari , Randall Wakefield , Michael Tanes , Miriam Dillard , Daniel Stewart , Jude Cancer Center Support Grant , Department Of Cell , Jude Children Research Hospital , National Cancer Institute , National Institutes Of Health , Jude Children , Research Hospital , Young Sang Ryu ,