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A novel 11 base pair deletion in KMT2C resulting in Kleefstra syndrome 2.

Haploinsufficiency of the Lysine Methyltransferase 2C (KMT2C) gene results in the autosomal dominant disorder, Kleefstra syndrome 2. It is an extremely rare neurodevelopmental condition, with 14 previous reports describing varied clinical manifestations including dysmorphic features, delayed psychomotor development and delayed growth.Here, we describe a female with global developmental delay, attention deficit disorder, dyspraxia, short stature ....

Wiley Periodicals , Lysine Methyltransferase , Molecular Genetics , Genomic Medicine ,

Comparative cross-sectional study of socio-psychological orthodontic needs and oral habits in Autism Spectrum Disorder.

This cross-sectional study analyzed the socio-psychological need for orthodontic treatment in children and adolescents with and without Autism Spectrum Disorder (ASD) and its association with deleterious oral habits.Children/adolescents aged 6-14 years old, with and without ASD, and their respective caregivers were included. Caregivers completed a questionnaire addressing children and adolescents' deleterious oral habits. To assess ....

Wiley Periodicals , Care Dentistry Association , Autism Spectrum Disorder , Orthodontic Treatment Needs ,

Expert Analysis: The Coming Storm - Insights After Nine Days of War in Israel

The ongoing war in Israel, driven by Iranian-backed proxy armies, highlights critical lessons in intelligence, deterrence, AI-driven warfare, and the imperative of moral clarity that America must heed to prepare for the challenges ahead. ....

United States , North Korea , United Kingdom , Gaza Strip , Ukraine General , Israel General , South Korea , City Of , Mediterranean Sea , Oceans General , North Korean , Svetlana Vlasova , Barak Ravid , Khaleda Rahman , Yuval Bazak , Gerald Ford , Vasco Cotovio , Yulia Kesaieva , Gabi Siboni , Richard Engel , David Israel , Naim Qassem , Douglas Murray , Jean Loup Samaan , Kim Ghattas , Alexander Smith ,

Escape history's failings, separate beauty from morality

In modern discourse, if beauty equates to moral and divine goodness, then what does that mean for those not considered beautiful? ....

United States , Lund University , Wiley Periodicals , Nazi Olympics ,