tonight, almost 60 million at risk of severe storms after a tornados ripped through parts of the midwest. plus relentless heat across the south. the ocean floor search for debris after a submersible imploded while seeking the titanic. the new investigations under way. three san antonio police officers charged with murder after shooting and killing a woman in her apartment. what her family is telling us. our one on one with florida governor ron desantis. the sharp border contrast he s drawing with former president trump and why he is trying to frame a big primary field as a two-man race. the new weight loss drug showing even more dramatic results than the ones out now. when it could be available. how colleges are preparing for a supreme court decision that c could bar thehem from using race in admissions. and the ultimate team player jumping in to save the day. announcer: this is nbc nightly news with lester holt. reporting tonight from aspen, colorado. good ev
Weight, more than 40 bounds in 24 weeks. nearly 60 pounds in 48 weeks. i started losing weight within about a month of being on the drug. reporter: jacynthia jesse was part of the trial. and while some patients were given a placebo she believes she was given retatrutide itself. i have to say it was life-changing, to lose almost 60 pounds, especially someone, again, almost 300 pounds. reporter: testing is in its early stages. a submission for fda approval is years away. but eli lilly is hopeful it will get approval for a different drug this year. the weight loss version of its approved diabetes medicine mounjaro. there are analysts who say it will be the most lucrative drug ever made. hyperbole? probably, yes. i think at lilly we try not to focus to go on which drugs are going to be really big sellers. what we try to focus on is are we making medicines that treat a