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PFS Benefit Observed With Tucatinib Plus T-DM1 in Previously Treated HER2+ Metastatic Breast Cancer

The addition of tucatinib to ado-trastuzumab emtansine (T-DM1) significantly improved progression-free survival vs placebo plus T-DM1 in patients with previously treated HER2-positive metastatic breast cancer, including those with brain metastases. ....

United States , San Antonio , Genentech Roche , Astra Zeneca , Eli Lilly , Alliance Foundation , Greenwich Life Sciences Inc , Phoenix Molecular Designs Ltd , Antonio Breast Cancer Symposium , Phoenix Molecular Designs , Quantum Leap , Tucatinib Plust Dm1 , T Dm1 , Ado Trastuzumab Emtansine , Phase 3 Her2climb 02 Trial , San Antonio Breast Cancer Symposium , Saraa Hurvitz , Fred Hutchinson Cancer Center ,

Tucatinib/Letrozole/Palbociclib Combination Demonstrates Meaningful Efficacy in HR+/HER2+ mBC

Treatment with the all-oral triplet of tucatinib, letrozole, and palbociclib yielded clinically meaningful efficacy results and had an acceptable safety profile in patients with hormone receptor–positive, HER2-positive metastatic breast cancer. ....

United States , National Cancer Institute , Clinical Cancer Research , Clinical Cancer , Breast Cancer , Neoadjuvant Her2 , Breast Cancer ,

Seagen: FDA Grants Accelerated Approval To Tukysa Combination For Colorectal Cancer Treatment

KENILWORTH (NJ) (dpa-AFX) - Seagen Inc. (SGEN) said Thursday that the U.S. Food and Drug Administration has granted accelerated approval to Tukysa (tucatinib) in combination with trastuzumab for ....

United States , Drug Administration , More Such Health News , Seagen Inc , Breakthrough Therapy Designation , Priority Review , Middle East , Latin America ,

Seagen Inc.: Seagen Announces Results from Pivotal MOUNTAINEER Trial Demonstrating Clinically Meaningful Antitumor Activity of TUKYSA (tucatinib) in Combination with Trastuzumab in Previously Treated HER2-Positive Metastatic Colorectal Cancer

-Phase 2 trial showed chemotherapy-free TUKYSA combination resulted in clinically meaningful and durable tumor responses- -Results presented in late-breaking oral session at the ESMO World Congress ....

United Kingdom , United States , Comunidad Autonoma De Cataluna , David Caouette , Roger Dansey , Peggy Pinkston , Johnh Strickler , Duke University School Of Medicine , World Congress On Gastrointestinal , World Congress On Gastrointestinal Cancer , Drug Administration , Lab Abnormalities , Seagen Inc , Exchange Commission , Approval Program , Corporate Communications , European Union , European Medicines Agency , European Society For Medical Oncology , American Cancer Society Journal , American Cancer Society , European Society , Medical Oncology , World Congress , Gastrointestinal Cancer , Associate Professor ,

Seagen Inc.: Seagen Announces Positive Topline Results of Pivotal Phase 2 Clinical Trial of TUKYSA (tucatinib) in Combination With Trastuzumab in HER2-Positive Metastatic Colorectal Cancer

- Data Accepted for Presentation at ESMO World Congress on Gastrointestinal Cancer - Seagen Inc. (Nasdaq:SGEN) today announced positive topline results from the pivotal phase 2 MOUNTAINEER clinical ....

United States , United Kingdom , Comunidad Autonoma De Cataluna , David Caouette , Roger Dansey , Peggy Pinkston , Johnh Strickler , Drug Administration , Lab Abnormalities , Seagen Inc , World Congress On Gastrointestinal Cancer , Exchange Commission , Approval Program , Duke University Medical Center , Corporate Communications , European Union , European Medicines Agency , European Society For Medical Oncology , American Cancer Society , Gastrointestinal Cancer , New Drug Application , Important Safety Information , Chief Medical Officer , European Society , Medical Oncology , World Congress ,