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Merck (MRK) and AstraZeneca (AZN) Present Final Results of Key Secondary Overall Survival Endpoint From Phase 3 PROpel Trial

Merck (MRK) and AstraZeneca (AZN) Present Final Results of Key Secondary Overall Survival Endpoint From Phase 3 PROpel Trial
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United statesJulie cunninghamManchester christie salfordDamini chokshiEliav barrSusan galbraithChrissy trankNoel clarkePeter dannenbaumManchester universityStatement of merck co incProstate cancer working groupMerck co incJapanese pharmaceuticalsEuropean unionMerck research laboratories

Merck & Co , Inc : LYNPARZA (olaparib) in Combination With Abiraterone and Prednisone or Prednisolone Approved in the EU as Treatment for Certain Patients With Metastatic Castration-Resistant Prostate Cancer

First PARP inhibitor and new hormonal agent combination approved for these patients in Europe AstraZeneca and Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced

United statesJulie cunninghamPeter dannenbaumDamini chokshiMichael mcardleEuropean commissionStatement of merck co incProstate cancer working groupMerck co incExchange commissionCommittee for medicinal products humanEuropean unionMedicinal productsHuman useAcute myeloid leukemiaThromboembolic events

LYNPARZA (olaparib) in Combination With Abiraterone and Prednisone or Prednisolone Receives Positive Opinion From EU CHMP as Treatment for Certain Patients With Metastatic Castration-Resistant Prostate Cancer

14.11.2022 - AstraZeneca and Merck (NYSE: MRK), known as MSD outside of the United States and Canada, today announced that the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending approval .

United statesStatement of merck co incMerck co incExchange commissionEuropean unionMerck co stockAcute myeloid leukemiaFetal toxicityThromboembolic eventsFirst line maintenanceAdvanced ovarianFirst line maintenance advanced ovarian cancerMaintenance recurrent ovarianAdjuvant treatmentHigh risk early breastNegative metastatic breast

AstraZeneca: LYNPARZA (olaparib) in Combination with Bevacizumab, and as a Monotherapy, Demonstrates Clinically Meaningful Survival Benefit in 1st-Line Advanced Ovarian Cancer Across Two Phase III Trials

Landmark 5-year follow-up of PAOLA-1 Phase III trial demonstrated LYNPARZA plus bevacizumab meaningfully extended survival with 65.5% of HRD-positive patients surviving 5 years vs. 48.4% treated with

Sao pauloUnited kingdomRhode islandUnited statesIsabelle ray coquardPaul disilvestroJessica mcduellBrendan mcevoyEliav barrSusan galbraithInvestigateurs national des etudes cancers ovariensNational cancer instituteMerck research laboratoriesEuropean network of gynaecological oncological trialEuropean society of medical oncologyResearch association de recherche

Merck (MRK) and AstraZeneca (AZN) Announces LYNPARZA Approved in Japan as Adjuvant Treatment for Patients With BRCA-Mutated, HER2-Negative High Recurrent Risk Breast Cancer

Merck (MRK) and AstraZeneca (AZN) Announces LYNPARZA Approved in Japan as Adjuvant Treatment for Patients With BRCA-Mutated, HER2-Negative High Recurrent Risk Breast Cancer
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United statesCity ofUnited kingdomDave fredricksonChrissy trankPeter dannenbaumAndrew tuttDamini chokshiMelissa moodyEliav barrKing college londonFrontier science technology research foundationStatement of merck co incBreast international groupMerck co incEuropean union