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New Biomarker Tests Could Reduce Need for Liver Biopsy

New biomarker tests identified NASH and related conditions at least as well as common lab tests, paving the way for blood-based alternatives to liver biopsy for clinical care and therapeutic trials.

Orexin Receptor 2 Agonist Improves Sleepiness in Narcolepsy

For patients with narcolepsy type 1, an orexin receptor 2 agonist, TAK-994, improves measures of sleepiness and cataplexy.

Orexin Receptor 2 Agonist Improves Sleepiness in Narcolepsy

For patients with narcolepsy type 1, TAK-994 improves measures of sleepiness and cataplexy over 8 weeks compared with placebo.

Orexin Receptor 2 Agonist Improves Sleepiness in Narcolepsy

Improvement seen in measures of sleepiness, cataplexy over eight weeks versus placebo, but drug was associated with hepatotoxic effects.

Orexin receptor 2 agonist improves sleepiness in narcolepsy