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Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

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Scientists find new form of Alzheimer's disease

Scientists find new form of Alzheimer's disease
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A Subset of Alzheimer's Cases May be Caused by Two Copies of a Single Gene, New Research Shows

A Subset of Alzheimer's Cases May be Caused by Two Copies of a Single Gene, New Research Shows
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Scientists identify new genetic form of Alzheimer's disease

A gene called APOE4 has long been considered a key risk factor. But new research says if people inherit two copies of that gene, it's not just a risk it.

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