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Panama’s Top 8 Retirement Destinations: The Ranking Of The 2021 Panama Index 8. Santiago Alamy/Sunshine Pics Where Is Santiago? Santiago is the bustling capital and the commercial and political center of the Veraguas province, as well as the transportation hub for Central Panama. It is also a university town renowned for training the future teachers of Panama. Santiago has been growing for several years now, but no one was paying attention as the creeping path of progress wound its way through this sleepy city. These days, Santiago is no longer an outpost in the middle of nowhere, it’s become a true regional hub in its own right. ....