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100-year-old brain mystery: What does the temporal pole do?

One part of the brain surface, a region called the temporal pole because it is at the very tip of the temporal lobe, could not be linked to a specific function for at least the first 100 years of research on the cortex. Northwestern Medicine scientists have just discovered that this mysterious and seemingly silent surface is actually one of the most colorful regions of the brain. It has critical functions in word comprehension, face recognition and the regulation of behavior.

Case study: Experimental lecanemab treatment causes adverse outcomes in 65-year-old woman with Alzheimer s disease

In a noteworthy case study published in the Journal of Alzheimer's Disease investigators report autopsy findings in a 65-year-old woman with Alzheimer's disease (AD) who received three open label infusions of the experimental anti-amyloid beta (Aβ) antibody drug lecanemab.

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