Scientists have reported the first evidence that our Earth and the universe around us are awash in a background of spacetime undulations called gravitational waves. The waves oscillate very slowly over years and even decades and are thought to originate primarily from pairs of supermassive black hol
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PHILADELPHIA Scientists in the Perelman School of Medicine at the University of Pennsylvania have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM), an often-fatal heart disorder.
This inherited form of DCM which affects at least several thousand people in the United States at any one time and often causes sudden death or progressive heart failure is one of multiple congenital disorders known to be caused by inherited mutations in a gene called
LMNA. The
LMNA gene is active in most cell types, and researchers have not understood why
LMNA mutations affect particular organs such as the heart while sparing most other organs and tissues.