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COVID-19 Vaccination Produces Significant Immune Response in Adults With Liver Disease

Three rounds of COVID-19 vaccination among patients with liver disease and liver transplantation results in robust immunogenicity. ....

United Kingdom , European Association , Observational Cohort , Vaccine Efficacy , Protective Immunity ,

Sonata Therapeutics Presents Data Supporting its Network Medicines™ Approach at SITC 2023

Sonata Therapeutics Presents Data Supporting its Network Medicines™ Approach at SITC 2023
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Francesco Marincola , Ryan Shaler , Volker Herrmann , Carolyn Noyes , Maria Cristina Munteanu , Sonata Therapeutics Inc , Champalimaud Foundation , Network Medicines , Sonata Proprietary Intrinsic Antigen Release Technology , San Diego Convention Center On , Sonata Network Medicines , Society For Immunotherapy Of Cancer , Intrinsic Antigen Release Technology , Proprietary Intrinsic Antigen Release Technology , Drives In Situ Generation , Potent Anti Tumor Immunity Across Warm , Cold Tumor Models , Protective Immunity , Murine Syngeneic Tumor Cell Line , Dual Approach , Direct Cytotoxicity , Defined Immune Activation , Exploring Novel Ferroptosis Inducer , Promising Strategy , Sarcoma Treatment , Chief Executive Officer ,

Inflammatory gene variant protects mice from kidney problems, pointing to new diagnostic tool

The discovery of a variant of an inflammatory gene that protects the kidneys in mice could unlock more personalized approaches to the treatment of humans. ....

New South Wales , Natasha Rogers , Garvan Institute Of Medical Research , University Of New South Wales , Kidney International , Garvan Institute , Medical Research , Westmead Hospital , Inflammatory Gene Variant , Kidney Disease , Diagnostic Tool , Acute Kidney Injury , Protective Immunity , Autoimmune Disease ,

"Genetic Variants and Protective Immunity against SARS-CoV-2" by Ali A. Rabaan, Abbas Al Mutair et al.

The novel coronavirus-19 (SARS-CoV-2), has infected numerous individuals worldwide, resulting in millions of fatalities. The pandemic spread with high mortality rates in multiple waves, leaving others with moderate to severe symptoms. Co-morbidity variables, including hypertension, diabetes, and immunosuppression, have exacerbated the severity of COVID-19. In addition, numerous efforts have been made to comprehend the pathogenic and host variables that contribute to COVID-19 susceptibility and pathogenesis. One of these endeavours is understanding the host genetic factors predisposing an individual to COVID-19. Genome-Wide Association Studies (GWAS) have demonstrated the host predisposition factors in different populations. These factors are involved in the appropriate immune response, their imbalance influences susceptibility or resistance to viral infection. This review investigated the host genetic components implicated at the various stages of viral pathogenesis, including viral en ....

Wide Association Studies , Covid 19 , Genetic Resistance , Protective Immunity ,

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers studied the immune responses in Syrian hamsters re-infected with SARS-CoV-2 Delta and B.1 variants three months after the primary infection. ....

Aimee Molineux , Neha Mathurmar , Neha Mathur , Journal Viruses , Protective Immunity , Reduces Disease Severity Post Re Infection , Delta Variants , Image Credit , Coronavirus Disease Covid 19 , Ars Cov 2 , Covid 19 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Tissue Culture ,